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05-23-0151 Oxytocin

Oxytocin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
05-23-0151
  
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Overview

Replacement Information
Description
Overview

This product has been discontinued.

We apologize for the inconvenience, but we do not currently have an alternative product.





Synthetic oxytocin. Principal uterus-contracting and lactation-stimulating hormone of posterior pituitary gland that causes a marked, but transient, relaxation of vascular smooth muscles. Induces differentiation of P19 embryonic stem cells to cardiomyocytes. Stimulates myometrial GTPase and phospholipase C via coupling to Gq/11α. Oxytocin is known to increase Na+ excretion.
Catalogue Number05-23-0151
Brand Family Calbiochem®
References
ReferencesPaquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.
Product Information
CAS number50-56-6
FormLyophilized
FormulationSupplied as an acetate salt. Sold on the basis of peptide content.
Hill FormulaC₄₃H₆₆O₁₂N₁₂S₂
Chemical formulaC₄₃H₆₆O₁₂N₁₂S₂
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Cys¹-Tyr-Ile-Gln-Asn-Cys⁶-Pro-Leu-Gly-NH₂ (disulfide bond: 1 → 6)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSRS7534000
Safety Information
R PhraseR: 20-62

Harmful by inhalation.
Possible risk of impaired fertility.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-23-0151 0

Documentation

Oxytocin Certificates of Analysis

TitleLot Number
05-23-0151

References

Reference overview
Paquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.

Citations

Title
  • Cecily V. Bishop and Fredrick Stormshak. (2006) Nongenomic Action of Progesterone Inhibits Oxytocin-Induced Phosphoinositide Hydrolysis and Prostaglandin F2{alpha} Secretion in the. Endocrinology 147, 937-942.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision18-September-2008 RFH
    DescriptionSynthetic oxytocin. Principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland that causes a marked but transient relaxation of vascular smooth muscles. Stimulates myometrial GTPase and phospholipase C via coupling to Gq/11α. Oxytocin is known to increase Na+ excretion.
    FormLyophilized
    FormulationSupplied as an acetate salt. Sold on the basis of peptide content.
    CAS number50-56-6
    RTECSRS7534000
    Chemical formulaC₄₃H₆₆O₁₂N₁₂S₂
    Peptide SequenceH-Cys¹-Tyr-Ile-Gln-Asn-Cys⁶-Pro-Leu-Gly-NH₂ (disulfide bond: 1 → 6)
    Purity≥95% by HPLC
    Solubility5% Acetic acid (1 mg/ml)
    Storage Protect from moisture
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    Toxicity Harmful & Carcinogenic / Teratogenic
    Merck USA index14 6979
    ReferencesPaquin, J., et al. 2002. Proc. Natl. Acad. Sci. USA In Press. Ku, C.Y., et al. 1995. Endocrinology 136, 1509.
    Citation
  • Cecily V. Bishop and Fredrick Stormshak. (2006) Nongenomic Action of Progesterone Inhibits Oxytocin-Induced Phosphoinositide Hydrolysis and Prostaglandin F2{alpha} Secretion in the. Endocrinology 147, 937-942.
    		•