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459620 Okadaic Acid, Sodium Salt - Calbiochem

Okadaic Acid, Sodium Salt, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.

Okadaic Acid, Sodium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: PP1, PP2
459620
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₄₄H₆₇O₁₃ · Na

Products

Catalogue NumberPackaging Qty/Pack
459620-25UG Hliníkový sud 25 μg
Description
OverviewWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
Catalogue Number459620
Brand Family Calbiochem®
References
ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Normura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.
Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
Cohen, P. 1989. Annu. Rev. Biochem. 58, 453.
Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 254 21435.
Haystead, T.A. et al. 1989. Nature 337, 78.
Product Information
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₄₄H₆₇O₁₃ · Na
Chemical formulaC₄₄H₆₇O₁₃ · Na
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationOkadaic Acid, Sodium Salt, is a water-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
Biological Information
Primary TargetPP1, PP2
Primary Target IC<sub>50</sub>10-15 nM, 0.1 nM against protein phosphatase 1, protein phosphatase 2A, respectively
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 23/24/25-38

Toxic by inhalation, in contact with skin and if swallowed.
Irritating to skin.
S PhraseS: 22-26-36/37/39-45

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Toxic
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
459620-25UG 04055977185300

Documentation

Okadaic Acid, Sodium Salt - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Okadaic Acid, Sodium Salt - Calbiochem Certificates of Analysis

TitleLot Number
459620

References

Reference overview
Gjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Normura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.
Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
Cohen, P. 1989. Annu. Rev. Biochem. 58, 453.
Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 254 21435.
Haystead, T.A. et al. 1989. Nature 337, 78.

Brochure

Title
Protein Phosphatases Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-December-2024 JSW
DescriptionWater-soluble analog of Okadaic Acid (Cat. No. 495604). Inhibits protein phosphatases 1 and 2A.
FormWhite to off-white solid
Chemical formulaC₄₄H₆₇O₁₃ · Na
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (20 mg/ml), Ethanol (20 mg/ml), or H₂O (1 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Toxic
ReferencesGjertsen, B.T., et al. 1994. J. Cell Sci. 107, 3363.
Kiguchi, K., et al. 1994. Cell Growth Differentiation 5, 995.
Ohaka, Y., et al. 1993. Biochem. Biophys. Res. Commun. 197, 916.
Gopalakrishna, R., et al. 1992. Biochem. Biophys. Res. Commun. 189, 950.
Kreienbuhl, P., et al. 1992. Blood 80, 2911.
Normura, M., et al. 1992. Biochemistry 31, 11915.
Song, Q., et al. 1992. J. Cell Physiol. 153, 550.
Tada, Y., et al. 1992. Immunopharmacol. 24, 17.
Cohen, P., et al. 1990. Trends Biochem. Sci. 15, 98.
Cohen, P. 1989. Annu. Rev. Biochem. 58, 453.
Cohen, P., and Cohen, P.T.W. 1989. J. Biol. Chem. 254 21435.
Haystead, T.A. et al. 1989. Nature 337, 78.