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482210 Nimesulide Analog, Compound 76 - CAS 1021926-22-6 - Calbiochem

482210
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Overview

Key Spec Table

CAS #Empirical Formula
1021926-22-6C₂₄H₃₂N₂O₄S

Products

Catalogue NumberPackaging Qty/Pack
482210-5MG 5 mg
Description
OverviewA cell-permeable sulfonanilide that is shown to exhibit an antiproliferative effect against three HER-2-positive breast cancer cell lines, SKBR-3, BT474 and MDA-MB-453 (IC50= 0.9, 2.2, and 4.0 µM, respectively), and affects two HER-2-negative breast cancer cell lines, MCF-7 and MDA-MB-231 only at much higher concentrations (IC50 = 22.1 and 19.6 µM, respectively). The compound is not expected to be a COX-2 inhibitor and its cellular target(s) and mechanism(s) of growth inhibition is yet to be seen.
Catalogue Number482210
Brand Family Calbiochem®
SynonymsN-(3-(2,5-dimethylbenzyloxy)-4-(N-methylmethylsulfonamido)phenyl)cyclohexanecarboxamide
References
ReferencesChen, B., et al. 2009. Biochem. Pharmacol. 77, 1787.
Su, B., et al. 2008. J. Comb. Chem. 10, 475.
Product Information
CAS number1021926-22-6
FormOff-white solid
Hill FormulaC₂₄H₃₂N₂O₄S
Chemical formulaC₂₄H₃₂N₂O₄S
Quality LevelMQ100
Biological Information
Purity≥95% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Global Trade Item Number
Catalogue Number GTIN
482210-5MG 04055977183504