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500005 Kyselina nikotínová

extra čistá Ph Eur,BP,USP

Kyselina nikotínová MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Niacin, 3-Pyridinecarboxylic acid

CAS #: 59-67-6 EC Number: 200-441-0 Molar Mass: 123.11 g/mol Chemical Formula: 3-(COOH)-C₅H₄N Hill Formula: C₆H₅NO₂ Grade: Ph Eur,BP,USP
500005
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
59-67-6200-441-0C₆H₅NO₂3-(COOH)-C₅H₄N123.11 g/molPh Eur,BP,USP

Products

Catalogue NumberPackaging Qty/Pack
5000059020 Kartónová krabica 20 kg
Description
Catalogue Number500005
SynonymsNiacin, 3-Pyridinecarboxylic acid
DescriptionNicotinic acid
References
Product Information
CAS number59-67-6
EC number200-441-0
GradePh Eur,BP,USP
Hill FormulaC₆H₅NO₂
Chemical formula3-(COOH)-C₅H₄N
Molar Mass123.11 g/mol
HS Code2936 29 00
Structure formula ImageStructure formula Image
Quality LevelMQ400
Applications
Biological Information
Physicochemical Information
Density1.473 g/cm3 (25 °C)
Flash point193 °C
Ignition temperature>365 °C Prach
Melting Point236.6 °C
pH value3.4 (10 g/l, H₂O, 20 °C)
Bulk density330 kg/m3
Solubility18 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Potkan > 5000 mg/kg
LD 50 dermalLD50 Potkan > 2000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H319: Spôsobuje vážne podráždenie očí.
Precautionary Statement(s)P264: Po manipulácii starostlivo umyte pokožku.
P280: Noste ochranné okuliare/ ochranu tváre.
P305 + P351 + P338: PO ZASIAHNUTÍ OČÍ: Niekoľko minút ich opatrne vyplachujte vodou. Ak používate kontaktné šošovky a je to možné, odstráňte ich. Pokračujte vo vyplachovaní.
P337 + P313: Ak podráždenie očí pretrváva: vyhľadajte lekársku pomoc/ starostlivosť.
Signal WordPozor
Storage class10 - 13 Iné kvapaliny a tuhé látky
WGKWGK 1 mierne ohrozujúce vody
Disposal4
Kvapalné organické kyseliny a roztoky v prípade potreby zrieďte a opatrne neutralizujte hydrogénuhličitanom sodným (kat. č. 106323) alebo hydroxidom sodným (kat. č. 106462). Pred vyliatím do nádoby D skontrolujte pH pomocou indikátorových prúžkov pH-Universal (kat. č. 109535).
Safety Information
Categories of dangerdráždivá
Product Usage Statements
Storage and Shipping Information
StorageSkladujte pri +15°C až +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (alkalimetric, calculated on dried substance)99.5 - 100.5 %
Assay (HPLC, calculated on dried substance)98.0 - 102.0 %
Identity (HPLC)passes test
Identity (IR-spectrum)passes test
Identity (Melting point)passes test
Identity (UV-absorption)passes test
Appearancewhite to almost white, crystalline powder
Melting point234 - 240 °C
Absorption ratio (A 237 / A 262)0.46 - 0.50
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
As (Arsenic)≤ 3 ppm
Pb (Lead)≤ 10 ppm
Cu (Copper)*≤ 25 ppm
Cu (Copper) (ICP)*≤ 25 ppm
Pd (Palladium)*≤ 1 ppm
Zn (Zinc)≤ 25 ppm
Residual solvents (ICH Q3C)excluded by production process
Related substances (HPLC) (largest single impurity)≤ 0.05 %
Related substances (HPLC, Ph Eur) (sum of all impurities)≤ 0.05 %
Related substances (HPLC) (Isocinchomeronic acid)≤ 0.05 %
Related substances (HPLC) (6-Hydroxynicotinic acid)≤ 0.05 %
Related substances (HPLC) (Isonicotinic acid)≤ 0.05 %
Related substances (HPLC) (6-Methylnicotinic acid)≤ 0.05 %
Related substances (HPLC) (6,6‘-Dinicotinic acid)≤ 0.05 %
Related substances (HPLC) (5-Nitronicotinic acid)≤ 0.05 %
Related substances (HPLC) (Pyridine)≤ 0.05 %
Related substances (HPLC) (3-Nitropyridine)≤ 0.05 %
Related substances (HPLC) (3,5-Dinitropyridine)≤ 0.05 %
Related substances (HPLC) (3-Ethylpyridine)≤ 0.05 %
Related substances (HPLC) (5-Ethyl-2-methylpyridine)≤ 0.05 %
Related substances (HPLC) (any unspecified impurity)≤ 0.05 %
Related substances (HPLC, USP) (sum of all impurities)≤ 0.20 %
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C, 1h)≤ 1.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur, BP, USP
Global Trade Item Number
Catalogue Number GTIN
5000059020 04022536255002

Documentation

Kyselina nikotínová MSDS

Title

Safety Data Sheet (SDS) 

Kyselina nikotínová Certificates of Analysis

Product Number PackagingSpecificationLot Number
5000059020 Kartónová krabicaPDF Specification Document

Certificates

Title