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480875 Neurotrophin-3, Human, Recombinant, E. coli

480875
  
Purchase on Sigma-Aldrich

Overview

Key Spec Table

Purity
≥98% by SDS-PAGE
Description
Overview

This product has been discontinued.





Recombinant, human neurotrophin-3 expressed in E. coli. A potent neurotrophic factor that supports the survival of certain CNS neurons. Increases DNA-binding of several transcription factors.
Catalogue Number480875
Brand Family Calbiochem®
SynonymsrhNT-3
References
ReferencesCarter, B.D., et al. 1996. Science 272, 542.
Iwata, E., et al. 1996. Biochim. Biophys. Acta 1311, 85.
Zhou, X.F., and Rush, R.A. 1994. Brain Res. 643, 162.
Hohn, A., et al. 1990. Nature 344, 339.
Mainsonpierre, P.C., et al. 1990. Science 247, 1447.
Product Information
FormLyophilized solid
Quality LevelMQ100
Biological Information
Biological activityFully biologically active when compared to native NT-3. EC₅₀ = 50 ng/ml for induction of choline acetyltransferase activity in rat basal forebrain primary septal culture cells
Purity≥98% by SDS-PAGE
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
480875 0