480066 Sigma-AldrichNecrostatin-1, Inactive Control - CAS 64419-92-7 - Calbiochem
Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties.
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Synonyms: 5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i
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Overview
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 64419-92-7 | C₁₂H₁₁N₃OS |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 480066-5MG | Plastová ampulka | 5 mg |
| Description | |
|---|---|
| Overview | A cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) that is devoid of anti-necroptotic properties and serves as a suitable inactive control. Note: This inactive inhibitor of necrosis should not be used in high concentration. |
| Catalogue Number | 480066 |
| Brand Family | Calbiochem® |
| Synonyms | 5-(Indol-3-ylmethyl)-2-thiohydantoin, Nec-1i |
| References | |
|---|---|
| References | Takahashi et al. 2012. Cell Death and Disease 3, e437. Degterev, A., et al. 2005. Nat. Chem. Biol. 1, 112. |
| Product Information | |
|---|---|
| CAS number | 64419-92-7 |
| ATP Competitive | N |
| Form | Light yellow crystalline solid |
| Hill Formula | C₁₂H₁₁N₃OS |
| Chemical formula | C₁₂H₁₁N₃OS |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications | |
|---|---|
| Application | Necrostatin-1, Inactive Control, CAS 64419-92-7, is a cell-permeable N-demethylated thiohydantoin analog of Nec-1 (Cat. No. 480065) without anti-necroptotic properties. |
| Biological Information | |
|---|---|
| Primary Target | Inactive control for Nec-1 (Cat. No. 480065) |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 480066-5MG | 04055977201888 |