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FCMAB203P Milli-Mark™ Anti-CD64-PE Antibody, clone 10.1

FCMAB203P
100 tests  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMPhycoerythrinMonoclonal Antibody
Description
Catalogue NumberFCMAB203P
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD64-PE Antibody, clone 10.1
Alternate Names
  • High affinity immunoglobulin gamma Fc receptor I
  • IgG Fc receptor I
  • Fc-gamma RIA
  • FcgammaRIa
  • Fc-gamma RI
  • FcRI
Background InformationCD64 is the high-affinity IgG Fc receptor belonging to the immunoglobulin supergene family (Guyre, 2002). CD64 is a 72 kDa glycoprotein which binds monomeric IgG (human IgG1>IgG3>>IgG4>>>IgG2 and mouse IgG3>IgG2a>>>IgG1, IgG2b). Three genes: FcγR1A, FcγR1B and FcγR1C, which have >98 percent identity at the nucleotide level, have been identified and mapped to chromosome 1, band q21.1 (Sun,1997)). The FcγR1A gene, which specified the high-affinity IgG receptor, encodes three C2-type Ig-like extracellular domains, a 21 amino acid transmembrane region, and a charge cytoplasmic tail of 61 amino acids (Sun, 1997)(van de Winkel,1993).
References
Product Information
FormatPhycoerythrin
Control
  • PBMC's
PresentationPurified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality LevelMQ100
Applications
ApplicationMilli-Mark Anti-CD64-PE Antibody, clone 10.1 detects level of CD64 & has been published & validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenHuman rheumatoid synovial fluid cells and monocytes.
Clone10.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD64 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 72 kDa (Sun W, 1997)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using human PBMCs
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCMAB203P 04053252412035

Documentation

Milli-Mark™ Anti-CD64-PE Antibody, clone 10.1 MSDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-CD64-PE Antibody, clone 10.1 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD64-PE, clone 10.1 - 2110550 2110550
Milli-Mark Anti-CD64-PE, clone 10.1 - NRG1781532 NRG1781532
Milli-Mark™ Anti-CD64-PE, clone 10.1 - 3247077 3247077
Milli-Mark™ Anti-CD64-PE, clone 10.1 - 3476012 3476012
Milli-Mark™ Anti-CD64-PE, clone 10.1 - 3817586 3817586
Milli-Mark™ Anti-CD64-PE, clone 10.1 - 4115104 4115104