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AG243 Midkine, recombinant human

AG243
20 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberAG243
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionMidkine, recombinant human
OverviewHuman Midkine (MK) is a new member of the heparin-binding neurotrophic factor family. MK and PTN (Pleiotrophin) are structural homologs, and are highly conserved among species. MK plays important roles in development and carcinogensis and has several important biological effects, including promotion of neurite extension and neuronal survival. Recombinant Midkine is a 13.4 kDa protein, comprising of 123 amino acid residues.
References
Product Information
PresentationLyophilized from 0.4x PBS, pH 7.4.
Quality LevelMQ100
Applications
Key Applications
  • Positive Control
Biological Information
PurityGreater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per mg of MK.
SourceE.coli
Entrez Gene Number
Gene Symbol
  • MDK
  • ARAP
  • FLJ27379
  • MK1
  • NEGF2
  • MK
  • midkine
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P21741 # Has heparin binding activity, and growth promoting activity. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
SIZE: 143 amino acids; 15585 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
SIMILARITY: SwissProt: P21741 ## Belongs to the pleiotrophin family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsThe lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into water or other buffered solutions. Reconstitute MK should be stored in undiluted aliquots at -20°C for up to 6 months.
Packaging Information
Material Size20 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AG243 04053252580970

Documentation

Midkine, recombinant human MSDS

Title

Safety Data Sheet (SDS) 

Midkine, recombinant human Certificates of Analysis

TitleLot Number
RECOMBINANT HUMAN MIDKINE 2943224
RECOMBINANT HUMAN MIDKINE 2477833
RECOMBINANT HUMAN MIDKINE 2900144
RECOMBINANT HUMAN MIDKINE - 2139997 2139997
RECOMBINANT HUMAN MIDKINE - 2002705 2002705
RECOMBINANT HUMAN MIDKINE - 2021703 2021703
RECOMBINANT HUMAN MIDKINE - 2048757 2048757
RECOMBINANT HUMAN MIDKINE - 2211009 2211009
RECOMBINANT HUMAN MIDKINE - 2325022 2325022
RECOMBINANT HUMAN MIDKINE - 2499547 2499547