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444228 MMP-7 Substrate, Fluorogenic - Calbiochem

444228
  
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Overview

Replacement Information
Description
Overview

This product has been discontinued.



Excellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1 s-1). The cleavage occurs at the Ala-Leu bond.

Catalogue Number444228
Brand Family Calbiochem®
SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
References
ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
Product Information
ATP CompetitiveN
FormYellow solid
Hill FormulaC₅₂H₇₇N₁₇O₁₄
Chemical formulaC₅₂H₇₇N₁₇O₁₄
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetFluorogenic substrate for MMP-7
Primary Target IC<sub>50</sub>kcat/Km = 1.9 x 105 M⁻¹ s⁻¹for MMP-7
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
444228 0

Documentation

MMP-7 Substrate, Fluorogenic - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

MMP-7 Substrate, Fluorogenic - Calbiochem Certificates of Analysis

TitleLot Number
444228

References

Reference overview
Welch, A.R., et al. 1996. Biochemistry 35, 10103.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-August-2008 RFH
SynonymsMatrilysin Substrate, PUMP-1 Substrate, DNP-RPLALWRS
DescriptionExcellent fluorogenic substrate for MMP-7 (kcat/Km = 1.9 x 105 M-1s-1). Excitation maximum: ~280 nm; emission maximum: ~360 nm. The cleavage occurs at the Ala-Leu bond.
FormYellow solid
Chemical formulaC₅₂H₇₇N₁₇O₁₄
Peptide SequenceDNP-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH
Purity≥90% by HPLC
Solubility10% Acetic acid (1 mg/ml)
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesWelch, A.R., et al. 1996. Biochemistry 35, 10103.
Welch, A.R., et al. 1995. Arch. Biochem. Biophys. 324, 59.