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538540 MMP-7, Proenzyme, Human, Recombinant, E. coli

MMP-7, Proenzyme, Human, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Promatrilysin, rhPro-MMP-7

538540
  
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Overview

Description
OverviewRecombinant, human pro-MMP-7 expressed in E. coli. MMP-7 is believed to be a key factor in the regulation of metastasis. Overexpression of MMP-7 is observed in colon cancer. Activatable by organomercurials (APMA; Cat. No. 164610).
Catalogue Number538540
Brand Family Calbiochem®
SynonymsPromatrilysin, rhPro-MMP-7
References
ReferencesGirolamo, N. D., et al. 2001. Invest. Ophtal. Visual. Sci. 42, 1963.
Kihira, Y., et al. 1996. Urol. Oncol. 2, 20.
Woessner, J.F. 1995. Methods Enzymol. 248, 485.
Crabbe, T., et al. 1992. Biochemistry 31, 8500.
Product Information
Unit of DefinitionOne unit is defined as the amount of enzyme that will digest 1.0 µg AZOCOLL™ Substrate (Cat. No. 194933), in the presence of 500 μM <i>p</i>-aminophenylmercuric acetate (APMA; Cat. No. 164610) per minute at 37°C, pH 7.5.
EC number3.4.24.23
FormLiquid
FormulationIn 150 mM NaCl, 25 mM Tris-HCl, 5 mM CaCl₂, 0.02% NaN₃, 0.01% BRIJ® 35 Detergent, pH 7.5.
Quality LevelMQ100
Biological Information
Specific Activity≥1400 units/mg protein (after activation)
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C). Freeze-thaw cycles may accelerate the activation process.
Global Trade Item Number
Catalogue Number GTIN
538540 0