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EI8 Leupeptin

EI8
100 mg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberEI8
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionLeupeptin
OverviewLeupeptin is an organic compound produced by actinomycetes, serine and cysteine proteases reversibly. Inhibits trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, Kallikrein, papain, thrombin, cathepsin B and trypsin.



MW:426.56 s 49.04 . 18.02 {C20H36N6O4 . ½H2SO4 . H2O}



Ac-Leu-Leu-Argininal (hemi-sulfated form). Thus material has three tautomeric isomers that can be visualized by chromatography.

Appearance: White amorphous powder

Working range 10-100μM. Stable for several hours in water. Stock solutions of 10mM in water are stable for 1 week at 4ºC and 6 months at -20ºC.

5mg/1.054 mL = 10mM. Typically dilute 1:100 for a 100μM working solution.

Source: Organic isolated from actinomycetes.
References
Product Information
HS Code2925 29 90
PresentationLyophilized.
Quality LevelMQ100
Applications
Key Applications
  • Inhibits Activity/Function
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain dry at -20ºC for up to 18 months after date of receipt. Store reconstituted product in aliquots at -20ºC for up to 6 months. Avoid repeated thaw freeze cycles.
Packaging Information
Material Size100 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
EI8 04053252741524

Documentation

Leupeptin MSDS

Title

Safety Data Sheet (SDS) 

Leupeptin Certificates of Analysis

TitleLot Number
LEUPEPTIN 3092540
LEUPEPTIN 2947367
LEUPEPTIN 3117782
LEUPEPTIN 3002877
LEUPEPTIN 2896402
LEUPEPTIN 2999843
LEUPEPTIN 2828624
LEUPEPTIN - 2385925 2385925
LEUPEPTIN - 2430330 2430330
LEUPEPTIN - 2015538 2015538

References

Reference overviewPub Med ID
The structure and activity of leupeptins and related analogs.
Maeda, K, et al.
J. Antibiot., 24: 402-4 (1971)  1970

4253693 4253693
Biological activities of leupeptins.
Aoyagi, T, et al.
J. Antibiot., 22: 558-68 (1969)  1969

4243683 4243683

Brochure

Title
Western Blotting Tools

Technical Info

Title
Protein Blotting Handbook: 6th Edition