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524615 L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt - Calbiochem

L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PI-3,4,5-P₃, 7NH₄, PIP₃, Dipalmitoyl-

524615
  
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₄₁H₇₅O₂₂P₄ · 7NH₄
Description
Overview

This product has been discontinued.



Activates Ca2+-insensitive PKC isozymes δ, ε, and η. Binds to the general receptor for phosphoinositide-1 (GRP1) protein through a plekstrin homology (PH) domain. Also reported to increase the motility of NIH/3T3 cells and produce actin reorganization and membrane ruffling.
Catalogue Number524615
Brand Family Calbiochem®
SynonymsPI-3,4,5-P₃, 7NH₄, PIP₃, Dipalmitoyl-
References
ReferencesDerman, M.P., et al. 1997. J. Biol. Chem. 272, 6465.
Klarlund, J.K., et al. 1997. Science 275, 1927.
Ireton, K., et al. 1996. Science 274, 780.
Toker, A., et al. 1994. J. Biol. Chem. 269, 32358.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₄₁H₇₅O₂₂P₄ · 7NH₄
Chemical formulaC₄₁H₇₅O₂₂P₄ · 7NH₄
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetCa2+-insensitive PKC isozymes δ, ε, and η
Purity≥98% by NMR
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Irritant
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
524615 0

Documentation

L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt - Calbiochem Certificates of Analysis

TitleLot Number
524615

References

Reference overview
Derman, M.P., et al. 1997. J. Biol. Chem. 272, 6465.
Klarlund, J.K., et al. 1997. Science 275, 1927.
Ireton, K., et al. 1996. Science 274, 780.
Toker, A., et al. 1994. J. Biol. Chem. 269, 32358.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-August-2008 RFH
SynonymsPI-3,4,5-P₃, 7NH₄, PIP₃, Dipalmitoyl-
DescriptionSynthetic. Activates Ca2+-insensitive PKC isotypes δ, ε, and η. Binds to the GRP1 protein through a plekstrin homology (PH) domain. Also reported to increase the motility of NIH 3T3 cells and produce actin reorganization and membrane ruffling.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₄₁H₇₅O₂₂P₄ · 7NH₄
Structure formulaStructure formula
Purity≥98% by NMR
SolubilityDMSO (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Irritant
ReferencesDerman, M.P., et al. 1997. J. Biol. Chem. 272, 6465.
Klarlund, J.K., et al. 1997. Science 275, 1927.
Ireton, K., et al. 1996. Science 274, 780.
Toker, A., et al. 1994. J. Biol. Chem. 269, 32358.