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401483 IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem

IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (5-Phenyl-2-ureido)thiophene-3-carboxamide

Primary Target: IKK-2
401483
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
354811-10-2C₁₂H₁₁N₃O₂S
Description
Overview

This product has been discontinued.



An ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
Catalogue Number401483
Brand Family Calbiochem®
Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
References
ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
Product Information
CAS number354811-10-2
ATP CompetitiveY
FormOff-white solid
Hill FormulaC₁₂H₁₁N₃O₂S
Chemical formulaC₁₂H₁₁N₃O₂S
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetIKK-2
Primary Target IC<sub>50</sub>13 nM
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
401483 0

Documentation

IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

IKK-2 Inhibitor VI - CAS 354811-10-2 - Calbiochem Certificates of Analysis

TitleLot Number
401483

References

Reference overview
Baxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-April-2011 RFH
Synonyms(5-Phenyl-2-ureido)thiophene-3-carboxamide
DescriptionAn ureido-thiophenecarboxamide compound that acts as a potent, cell-permeable, reversible, and ATP-competitive inhibitor of IKK-2 (IC50 = 13 nM).
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number354811-10-2
Chemical formulaC₁₂H₁₁N₃O₂S
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Carcinogenic / Teratogenic
ReferencesBaxter, A., et al. 2004. Bioorg. Med. Chem. Lett. 14, 2817.