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EZHS100B-33K Human S100B ELISA, EZHS100B-33K

EZHS100B-33K
96-well strip plate  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey Applications
S100B HELISA
Description
Catalogue NumberEZHS100B-33K
DescriptionHuman S100B ELISA, EZHS100B-33K
OverviewEMD Millipore’s Human S100B ELISA kit is to be used for the quantification of human S100B in cerebrospinal fluid, serum and plasma. This kit has not been tested for cell culture supernatants.
Background InformationS100B is a calcium-binding protein produced mainly by astrocytes in the central nervous system and has been implicated in the development and maintenance of the nervous system. Although the mechanism of S100B secretion is unknown, it appears to be affected by oxidative stress. At nanomolar concentrations (normal levels), S100B is able to protect neurons against glutamate toxicity. Glial damage or astrocytic reactions to neural injury (reactive astrogliosis) causes an increase in S100B to micromolar concentrations. High levels of S100B will further increase neuronal damage. High levels of S100B are considered a biomarker that could indicate damage or dysfunction of CNS.
References
Product Information
HS Code3002 15 90
Precision, %
  • Intra-assay: <4%
  • Inter-assay: <4%
Quality LevelMQ200
Applications
ApplicationThis Human S100B ELISA kit is to be used for the quantification of human S100B in cerebrospinal fluid, serum & plasma.
Key Applications
  • ELISA
Application NotesThis is a same day assay
Biological Information
SpecificityThe antibody pair used in this assay measures Human S100B and has no cross-reactivity with S100A1, S100A6 and S100A13.

This assay detects S100B in multiple species, including: bovine, hamster, horse, monkey, mouse, pig, rabbit, and rat.
Species Reactivity
  • Human
Analytes Available
  • S100B
UniProt Number
Accuracy
  • 93% (CSF)
  • 94% (serum)
Physicochemical Information
Sensitivity
  • 2.7 pg/mL
Linearity of DilutionContact Technical Service for this information
Standard Curve Range
  • 2.7 – 2000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size96-well strip plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
EZHS100B-33K 04053252417313

Documentation

Protocols

Title
Protocol- EZHS100B-33K

Human S100B ELISA, EZHS100B-33K MSDS

Title

Safety Data Sheet (SDS) 

Brochure

Title
A closer look at immunoassay platforms. Beyond fit for purpse. Bring your biomarkers to life with Immunoassay Platform Solutions.
Custom Immunoassay Menu of Services

Technical Info

Title
96 well Template 2 Up
96 well Template Single
Quality Control Range Sheet- S100B-114 and S100B-214
S100B as a Biomarker for Ca2+ Signaling Dysregulation in Schizophrenia White Paper

Data Sheet

Title
Full Service Custom-built Assays