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371543 Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem

Non-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.

Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GDP-β-S, 3Li

371543
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
97952-36-8C₁₀H₁₂N₅O₁₀P₂S . 3Li
Description
OverviewNon-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.
Catalogue Number371543
Brand Family Calbiochem®
SynonymsGDP-β-S, 3Li
References
ReferencesPiacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.
Product Information
CAS number97952-36-8
FormWhite solid
Hill FormulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
Chemical formulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥85% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions lose 5% of their activity after 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
371543 0

Documentation

Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem Certificates of Analysis

TitleLot Number
371543

References

Reference overview
Piacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsGDP-β-S, 3Li
DescriptionA nonhydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs.
FormWhite solid
CAS number97952-36-8
Chemical formulaC₁₀H₁₂N₅O₁₀P₂S . 3Li
Structure formulaStructure formula
Purity≥85% by HPLC
SolubilityH₂O (50 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions lose 5% of their activity after 6 months at -20°C.
Toxicity Standard Handling
ReferencesPiacentini, L., et al. 1996. Biochim. Biophys. Acta 1282, 11.
Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J. 279, 447.
Silk, S.T., et al. 1989. J. Biol. Chem. 264, 21466.
Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA 84, 6374.
Gilman, A.G. 1987. Annu. Rev. Biochem. 56, 615.
Eckstein, F., et al. 1979. J. Biol. Chem. 254, 9829.