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356780 Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem

Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV). It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.

Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Glycyrrhizic Acid, NH₄+

356780
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
53956-04-0C₄₂H₆₁O₁₆ • NH₄
Description
OverviewA triterpenoid saponin isolated from liquorice roots that displays antiviral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably via its ability to upregulate nitric oxide synthase activity. Reported to block the growth of other viruses, including herpes virus, and helps restore liver functions in patients with hepatitis C. It is allso a known 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2) inhibitor.
Catalogue Number356780
Brand Family Calbiochem®
SynonymsGlycyrrhizic Acid, NH₄+
References
ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
Product Information
CAS number53956-04-0
FormWhite to off-white solid
Hill FormulaC₄₂H₆₁O₁₆ • NH₄
Chemical formulaC₄₂H₆₁O₁₆ • NH₄
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSLZ6500000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
356780 0

Documentation

Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Glycyrrhizin, Ammonium Salt - CAS 53956-04-0 - Calbiochem Certificates of Analysis

TitleLot Number
356780

References

Reference overview
Cinatl, J., et al. 2003. Lancet 361, 2045.
Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-January-2017 JSW
SynonymsGlycyrrhizic Acid, NH₄+
DescriptionA triterpenoid saponin, isolated from liquorice roots, that exhibits anti-viral and anti-tumor activities. Inhibits replication, adsorption, and penetration of severe acute respiratory syndrome-associated coronavirus (SARS-CV), presumably as a result of its ability to upregulate nitric oxide synthase activity. Also reported to hamper the growth of other viruses, including herpes virus. Shown to restore liver function in patients with hepatitis C virus (HCV). Also shown to inhibit 11β-hydroxysteroid dehydrogenase type 2 (11-HSD2).
FormWhite to off-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number53956-04-0
RTECSLZ6500000
Chemical formulaC₄₂H₆₁O₁₆ • NH₄
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityAqueous NH₄OH (50 mg/ml)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 4505
ReferencesCinatl, J., et al. 2003. Lancet 361, 2045.
Tanahashi, T., et al. 2002. J. Steroid Biochem. Mol. Biol. 80, 441.
Kondo, Y., and Takano, F. 1994. Biol. Pharm. Bull. 17, 759.