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109204 Giemsova azúrová eozín-metylénová modrá, roztok

for microscopy

Giemsova azúrová eozín-metylénová modrá, roztok MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
109204
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
1092040100 Sklená flaša 100 ml
1092040500 Plastová flaša 500 ml
1092041000 Plastová flaša 1 l
1092042500 Plastová flaša 2.5 l
Description
Catalogue Number109204
DescriptionGiemsa's azur-eosin-methylene blue solution
OverviewGiemsa’s Azure Eosin Methylene Blue solution - for microscopy, can be used for the staining of blood and bone marrow smears, paraffin sections and clinical-cytological specimens. Giemsa staining is one of the standard procedures in histology, demonstrating various cells with their morphological features better than with H&E stain. When used in hematological applications, Giemsa’s stain is frequently used in combination with other staining solutions, e. g. with May-Grünwald’s solution for Pappenheim (MGG) overview staining. This ready-to-use staining solution generally stains the nuclei red, based on the molecular interaction between the eosin Y dye and an Azure B-DNA complex. Both dyes assemble to an Eosin Y - Azure B-DNA complex and the intensity of the resulting stain depends on the content of Azure B and the ratio of Azure B : Eosin Y. Furthermore, the resulting stain can vary depending on the influence of fixation, staining times, pH-value of the solutions or buffer substances. In histology and clinico-cytological applications, Giemsa’s staining without additional stainings is used as an extended overview staining method. In this method, the color of the various cell components is influenced by pretreatment of the specimen material. Here, chromatin-containing structures (e. g. cell nuclei) appear in various blue shades, while the acidophilic components show up in a variety of red shades. The 500 ml bottle is sufficient for 3500-5000 stainings. This product is registered as IVD and CE marked. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
References
Product Information
HS Code3212 90 90
Quality LevelMQ400
Applications
Applicationfor microscopy
Biological Information
Physicochemical Information
Boiling point>65 °C (1013 hPa)
Density0.99 g/cm3 (20 °C)
Explosion limit5.5 - 44 %(V) Metanol
Flash point18 °C
Ignition temperature455 °C
pH value6.0 - 8.2 (H₂O, 20 °C) (neriedený)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H225: Veľmi horľavá kvapalina a pary.
H301 + H311 + H331: Toxický pri požití, styku s kožou alebo pri vdýchnutí.
H317: Môže vyvolať alergickú kožnú reakciu.
H370: Spôsobuje poškodenie orgánov.
Precautionary Statement(s)P210: Uchovávajte mimo dosahu tepla, horúcich povrchov, iskier, otvoreného ohňa a iných zdrojov zapálenia. Nefajčite.
P233: Nádobu uchovávajte tesne uzavretú.
P280: Použite ochranné rukavice/ ochranný odev/ ochranu očí/ ochranu tváre/ ochranu sluchu.
P301 + P310: PO POŽITÍ: Okamžite volajte TOXIKOLOGICKÉ INFORMAČNÉ CENTRUM/lekára.
P303 + P361 + P353: PRI KONTAKTE S POKOŽKOU (alebo vlasmi): Vyzlečte všetky kontaminované časti odevu. Pokožku ihneď opláchnite vodou.
P304 + P340 + P311: PO VDÝCHNUTÍ: Presuňte osobu na čerstvý vzduch a umožnite jej pohodlne dýchať. Volajte TOXIKOLOGICKÉ INFORMAČNÉ CENTRUM/lekára.
P403 + P233: Uchovávajte na dobre vetranom mieste. Nádobu uchovávajte tesne uzavretú.
Signal WordNebezpečenstvo
Storage class3 Vznietlivé kvapaliny
WGKWGK 2 významne ohrozuje vodné zdroje
Disposal9
Karcinogénne zlúčeniny a horľavé zlúčeniny označené ako "veľmi jedovaté" alebo "jedovaté": nádoba F. Alkylsulfáty sú karcinogénne. Buďte osobitne opatrní, aby nedošlo k vdýchnutiu alebo ku kontaktu s pokožkou. Alkylsulfáty neutralizujte pridaním (z oddeľovacieho lievika) koncentrovaného ľadového roztoku amoniaku (kat. č. 105426) po kvapkách za intenzívneho miešania. Pred vyliatím do nádoby D skontrolujte pH pomocou indikátorových prúžkov pH-Universal (kat. č. 109535).
Safety Information
Categories of dangerve?mi hor?avá, jedovatá
Product Usage Statements
Storage and Shipping Information
StorageSkladujte pri +15°C až +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1230 , 3 (6.1), II
Declaration (transport by air) IATA-DGRUN 1230 , 3 (6.1), II
Declaration (transport by sea) IMDG-CodeUN 1230 , 3 (6.1), II
Supplemental Information
Specifications
Suitability for microscopypasses test
Erythrocytesreddish-brownish
Nuclei / Chromatinred to violet
Eosinophilic granulesreddish to red-brown
Neutrophilic granuleslight violet
Lymphocyte cytoplasmnblue
Monocyte cytoplasmgrey-blue
Thrombocytesviolet
Basophilic granulesdark violet
Nuclei (Tissue section)blue to dark blue
Cellsblue to dark blue
Collagenpale blue
Osteoidpale blue
Eosinophilic granula (Tissue section)red
Acidic mucopolysaccharidesreddish-violet
Mast cell granulesreddish-violet
Cartilage matrixreddish-violet
Acidophilic materialsorange-red
Helicobacter pylori
blue to dark blue
blue to dark blue
Global Trade Item Number
Catalogue Number GTIN
1092040100 04022536111841
1092040500 04022536111889
1092041000 04022536720081
1092042500 04022536111926

Documentation

Giemsova azúrová eozín-metylénová modrá, roztok MSDS

Title

Safety Data Sheet (SDS) 

Giemsova azúrová eozín-metylénová modrá, roztok Certificates of Analysis

Product Number PackagingSpecificationLot Number
1092040100 Sklená flašaPDF Specification Document
1092040500 Plastová flašaPDF Specification Document
1092041000 Plastová flašaPDF Specification Document
1092042500 Plastová flašaPDF Specification Document

User Guides

Title
User Guide (IFU) - 109204

Related Products & Applications

Related Products

Catalogue Number Description
109203 Giemsova azúrová eozín-metylénová modrá

Accessories (Primary)

Catalogue Number Description
101424 May-Grünwaldova eozín-metylénová modrá, roztok, modifikovaný
101728 OSTEOSOFT®
101736 OSTEOMOLL®
106009 Metanol
109016 Neo-Mount™
109468 Pufrovacie tablety pH 7,2
109634 2-Propanol
109843 Neo-Clear™
111374 Pufrovacie tablety pH 6,8

Accessories (Secondary)

Catalogue Number Description
101424 May-Grünwaldova eozín-metylénová modrá, roztok, modifikovaný

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Categories

IVD/OEM Materials & Reagents > Microscopy > Hematology > Rapid Stainings, Hemacolor®
IVD/OEM Materials & Reagents > Microscopy > Histology > Histological Staining Solutions
IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents
IVD/OEM Materials & Reagents > Microscopy > Hematology > Hematological Staining Solutions
IVD/OEM Materials & Reagents > Microscopy > Bacteriology > General Bacteriological Staining Solutions