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345802 Gc-Globulin, Mixed Type, Human Plasma

345802
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
345802-1MG Plastová ampulka 1 mg
Description
OverviewNative Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.
Catalogue Number345802
Brand Family Calbiochem®
SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
References
ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology 7, 825.
Machii, T., et al. 1986. Acta Haematol. 75, 26.
Product Information
CAS number68476-36-8
FormSolid
FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
Quality LevelMQ100
Applications
ApplicationGc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
345802-1MG 04055977194050

Documentation

Gc-Globulin, Mixed Type, Human Plasma MSDS

Title

Safety Data Sheet (SDS) 

Gc-Globulin, Mixed Type, Human Plasma Certificates of Analysis

TitleLot Number
345802

References

Reference overview
Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology 7, 825.
Machii, T., et al. 1986. Acta Haematol. 75, 26.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-June-2008 RFH
SynonymsDBP, Vitamin D Binding Protein, Group-specific Component
DescriptionNative Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.
FormSolid
FormulationLyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number68476-36-8
Purity≥95% by SDS-PAGE
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
Toxicity Standard Handling
ReferencesDi Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology 7, 825.
Machii, T., et al. 1986. Acta Haematol. 75, 26.