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05-23-1701 FR-1

FR-1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CRGDSPASSC, Cyclic

Primary Target: ADP-induced platelet aggregation
05-23-1701
  
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₅H₅₇N₁₃O₁₆S₂
Description
Overview

This product has been discontinued.





A cyclic peptide containing the cell binding domain Arg-Gly-Asp and the associated cell migration sequence Pro-Ala-Ser-Ser of fibronectin. A potent inhibitor of ADP-induced platelet aggregation (IC50 = 7.6 µM).
Catalogue Number05-23-1701
Brand Family Calbiochem®
SynonymsCRGDSPASSC, Cyclic
References
ReferencesKatow, H., et al. 1997. Dev. Growth Differ. 39, 207.
Yamamoto, Y., et al. 1995. Chem. Lett. 11.
Product Information
FormWhite to off-white lyophilized solid
Hill FormulaC₃₅H₅₇N₁₃O₁₆S₂
Chemical formulaC₃₅H₅₇N₁₃O₁₆S₂
Hygroscopic Hygroscopic
Sold on the basis of peptide contentY
Applications
Biological Information
Primary TargetADP-induced platelet aggregation
Primary Target IC<sub>50</sub>7.6 µM
Purity≥97% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Cys¹-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys¹⁰-OH (disulfide bond: 1 → 10)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-23-1701 0

Documentation

FR-1 Certificates of Analysis

TitleLot Number
05-23-1701

References

Reference overview
Katow, H., et al. 1997. Dev. Growth Differ. 39, 207.
Yamamoto, Y., et al. 1995. Chem. Lett. 11.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
SynonymsCRGDSPASSC, Cyclic
DescriptionA cyclic peptide containing the cell binding domain Arg-Gly-Asp and associated cell migration Pro-Ala-Ser-Ser sequences of fibronectin. A potent inhibitor of ADP-induced platelet aggregation (IC50 = 7.6 µM).
FormWhite to off-white lyophilized solid
Chemical formulaC₃₅H₅₇N₁₃O₁₆S₂
Peptide SequenceH-Cys¹-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys¹⁰-OH (disulfide bond: 1 → 10)
Purity≥97% by HPLC
Solubility5% Acetic acid (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesKatow, H., et al. 1997. Dev. Growth Differ. 39, 207.
Yamamoto, Y., et al. 1995. Chem. Lett. 11.