Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

324903 Epiregulin, Human, Recombinant

Epiregulin, Human, Recombinant, consists of amino acids 63-108 and expressed in E. coli with an N-terminal methionine.

Epiregulin, Human, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
324903
  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Purity
≥97% by SDS-PAGE
Description
OverviewRecombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
Catalogue Number324903
Brand Family Calbiochem®
References
ReferencesMishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1997. Biochem. J. 326, 69.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Product Information
FormSolid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324903 0

Documentation

Epiregulin, Human, Recombinant MSDS

Title

Safety Data Sheet (SDS) 

Epiregulin, Human, Recombinant Certificates of Analysis

TitleLot Number
324903

References

Reference overview
Mishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1997. Biochem. J. 326, 69.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-Sepmtember-2011 RFH
DescriptionRecombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
FormSolid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg protein
Biological activityED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
SolubilityReconstitute to 100 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesMishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1997. Biochem. J. 326, 69.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.