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GF171 Endostatin Protein, Human Recombinant

The Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.

Endostatin Protein, Human Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P39060
GF171
100 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
E. coli.Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF171
DescriptionEndostatin Protein, Human Recombinant
Alternate Names
  • Collagen Type XVIII
  • Collagen alpha-1 (XVIII)
Background InformationEndostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is expressed in various organs with the highest levels in liver, lung and kidney. Endostatin inhibits angiogenesis by blocking the pro-angiogenic activities of VEGF and FGF-basic. Recombinant human Endostatin is a 20.2 kDa protein consisting 184 amino acid residues.
References
Product Information
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationThe Endostatin protein is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli.
Cross ReactivityNone
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Measured by its ability to inhibit HUVEC migration.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF171 04053252691362

Documentation

Endostatin Protein, Human Recombinant MSDS

Title

Safety Data Sheet (SDS) 

Endostatin Protein, Human Recombinant Certificates of Analysis

TitleLot Number
IL-22, Human Recombinant Animal Free - Q2444293 Q2444293
Recombinant Human Endostatin - 2370026 2370026
Recombinant Human Endostatin - 2388331 2388331
Recombinant Human Endostatin - 2437312 2437312
Recombinant Human Endostatin - 2460179 2460179
Recombinant Human -2538292 2538292
Recombinant Human -2800518 2800518
Recombinant Human Endostatin - 2316550 2316550
Recombinant Human Endostatin - 2326960 2326960
Recombinant Human Endostatin - 2328030 2328030
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Brochure

Title
New Products: Volume 3, 2012

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Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors