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324745 Elastase Inhibitor III - Calbiochem

The Elastase Inhibitor III controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Elastase Inhibitor III - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: HLE Inhibitor, MeOSuc-AAPV-CMK

Primary Target: Human leukocyte elastase (HLE)
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₂H₃₅ClN₄O₇
Description
OverviewA potent irreversible inhibitor of human leukocyte elastase (HLE)(Ki = 10 µM). Protects against lung injury induced by instillation of elastase.
Catalogue Number324745
Brand Family Calbiochem®
SynonymsHLE Inhibitor, MeOSuc-AAPV-CMK
References
ReferencesFletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₂H₃₅ClN₄O₇
Chemical formulaC₂₂H₃₅ClN₄O₇
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetHuman leukocyte elastase (HLE)
Primary Target K<sub>i</sub>10 µM against human leukocyte elastase (HLE)
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-CMK
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324745 0

Documentation

Elastase Inhibitor III - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Elastase Inhibitor III - Calbiochem Certificates of Analysis

TitleLot Number
324745

References

Reference overview
Fletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-October-2007 RFH
SynonymsHLE Inhibitor, MeOSuc-AAPV-CMK
DescriptionA potent inhibitor of human leukocyte elastase (HLE) (Ki = 10 µM).
FormWhite solid
Chemical formulaC₂₂H₃₅ClN₄O₇
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-CMK
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityDMSO (10 mg/ml) or Methanol
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesFletcher, D.S., et al. 1990. Am. Rev. Respir. Dis. 141, 672.
Stein, R.L., and Trainor, D.A. 1986. Biochemistry 25, 5414.
Powers, J.C., et al. 1977. Biochim. Biophys. Acta 485, 15.