253500 Sigma-AldrichDenbufylline
A cell-permeable xanthine derivative that acts as a selective inhibitor of phosphodiesterase IV (PDE IV; Ki = ~ 1 µM).
More>> A cell-permeable xanthine derivative that acts as a selective inhibitor of phosphodiesterase IV (PDE IV; Ki = ~ 1 µM). Less<<Denbufylline MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 1,3-Di-n-butyl-7-(2ʹ-oxopropyl)xanthine
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 57076-71-8 | C₁₆H₂₄N₄O₃ |
| Product Information | |
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| CAS number | 57076-71-8 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₁₆H₂₄N₄O₃ |
| Chemical formula | C₁₆H₂₄N₄O₃ |
| Reversible | N |
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| Applications |
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| Biological Information | |
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| Primary Target | Phosphodiesterase IV (PDE IV) |
| Primary Target K<sub>i</sub> | ~ 1 µM against PDE IV |
| Purity | ≥97% by HPLC |
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| Cell permeable | Y |
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| Safety Information according to GHS | |
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| RTECS | UO8413435 |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 253500 | 0 |
Documentation
Denbufylline MSDS
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Denbufylline Certificates of Analysis
| Title | Lot Number |
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| 253500 |
References
| Reference overview |
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| Kumari, M., et al. 1997. Br. J. Pharmacol. 121, 459. Sanae, F., et al. 1996. J. Pharmacol. Exp. Ther. 277, 54. Cortijo, J., et al. 1993. Br. J. Pharmacol. 108, 562. Nicholson, C.D., et al. 1989. Br. J. Pharmacol. 97, 889. |
Brochure
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| Activators and Inhibitors of Adenylate Cyclase Technical Bulletin |