268320 MilliporeDaptomycin, Streptomyces sp. - CAS 103060-53-3 - Calbiochem
A semi-synthetic cyclic polypeptide antibiotic that is active against vancomycin-resistant gram-positive bacteria, including enterococci and Staphylococcus aureus (MIC₅₀ = 0.13 µg/ml).
More>> A semi-synthetic cyclic polypeptide antibiotic that is active against vancomycin-resistant gram-positive bacteria, including enterococci and Staphylococcus aureus (MIC₅₀ = 0.13 µg/ml). Less<<Daptomycin, Streptomyces sp. - CAS 103060-53-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Cubicin, Dapcin
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 103060-53-3 | C₇₂H₁₀₁N₁₇O₂₆ |
| Description | |
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| Overview | A semi-synthetic cyclic polypeptide antibiotic that is active against vancomycin-resistant gram-positive bacteria, including enterococci and Staphylococcus aureus (MIC50 = 0.13 µg/ml). Its bactericidal activities have been attributed to its role in disruption of membrane potential and increased efflux of potassium ions from bacterial cells, which lead to disruption of protein, DNA, and RNA synthesis. Exhibits superior bactericidal properties compared to vancomycin (Cat. No. 627850) even in the presence of serum. |
| Catalogue Number | 268320 |
| Brand Family | Calbiochem® |
| Synonyms | Cubicin, Dapcin |
| Product Information | |
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| CAS number | 103060-53-3 |
| Form | Off-white to pale yellow solid |
| Hill Formula | C₇₂H₁₀₁N₁₇O₂₆ |
| Chemical formula | C₇₂H₁₀₁N₁₇O₂₆ |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥98% by HPLC |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 268320 | 0 |
Documentation
Daptomycin, Streptomyces sp. - CAS 103060-53-3 - Calbiochem MSDS
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Daptomycin, Streptomyces sp. - CAS 103060-53-3 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 268320 |
References
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| Kosmidis, C. and Levine, D.P., 2010. Expert Opin. Pharmacother. 11, 615. Cui, L., et al. 2006. Antimicrob. Agents Chemother. 50, 1079. Silverman, J.A., et al. 2003. Antimicrob. Agents Chemother. 47, 2538. Rybak, M.J., et al. 2000. Antimicrob. Agents Chemother. 44, 1062. |
Brochure
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| New Products: Volume 3, 2012 |