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268298 DAPI, Dihydrochloride - CAS 28718-90-3 - Calbiochem

Cell-permeable DNA-binding dye.

DAPI, Dihydrochloride - CAS 28718-90-3 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4ʹ,6-Diamidino-2-phenylindole, 2HCl

268298
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Overview

Key Spec Table

CAS #Empirical Formula
28718-90-3C₁₆H₁₅N₅ · 2HCl

Products

Catalogue NumberPackaging Qty/Pack
268298-10MG Plastová ampulka 10 mg
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Description
OverviewCell-permeable DNA-binding dye. Binds preferentially to DNA rich in adenine and thymine. Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes. Useful for microscopic detection of nuclei and nuclear DNA in normal and apoptotic cells. Can also be used to detect mycoplasma. A reversible inhibitor of S-adenosyl-L-methionine decarboxylase and diamine oxidase. Also available as a 5 mg/ml mM solution in H2O (Cat. No. 508741).
Catalogue Number268298
Brand Family Calbiochem®
Synonyms4ʹ,6-Diamidino-2-phenylindole, 2HCl
References
ReferencesMathieu, C., et al. 1995. Exp. Cell Res. 216, 13.
Cubria, C., et al. 1994. Comp. Biochem. Physiol. C. 105, 251.
Hotz, M.A., et al. 1994. Cytometry 15, 237.
Lee, L.S., and Garnett, H.M. 1993. J. Biochem. Biophys. Methods 26, 249.
Miller, T., et al. 1993. Biotechniques 15, 1042.
Gray, J.W., et al. 1982. Science 238, 323.
Hessling, J.J., et al. 1980. J. Immunol. Methods 38, 315.
Russels, W.C., et al. 1975. Nature 253, 461.
Product Information
CAS number28718-90-3
ATP CompetitiveN
FormYellow solid
Hill FormulaC₁₆H₁₅N₅ · 2HCl
Chemical formulaC₁₆H₁₅N₅ · 2HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetBinds preferentially to DNA rich in adenine and thymine
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Safety Information according to GHS
RTECSNL5995050
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 6 weeks at 4°C or for up to 6 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
268298-10MG 04055977197785