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137002 Kyselina citrónová

bezvodý prášok, vhodná pre biofarmaceutickú výrobu EMPROVE® EXPERT Ph Eur,BP,ChP,JP,USP

Kyselina citrónová MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

CAS #: 77-92-9 EC Number: 201-069-1 Molar Mass: 192.12 g/mol Chemical Formula: (HOOCCH₂)₂C(OH)COOH Hill Formula: C₆H₈O₇ Grade: Ph Eur,BP,ChP,JP,USP
137002
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-92-9201-069-1C₆H₈O₇(HOOCCH₂)₂C(OH)COOH192.12 g/molPh Eur,BP,ChP,JP,USP

Products

Catalogue NumberPackaging Qty/Pack
1370020001 Kartónová krabica 3 x 1 kg
1370021000 Plastová flaša 1 kg
1370025000 Plastová flaša 5 kg
1370029012 Plastové vedro 12 kg
1370029029 Dvojité PE vrecko 25 kg
1370029500 Big Bag 500 kg
Description
Catalogue Number137002
Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
DescriptionCitric acid
References
Product Information
CAS number77-92-9
EC number201-069-1
GradePh Eur,BP,ChP,JP,USP
Hill FormulaC₆H₈O₇
Chemical formula(HOOCCH₂)₂C(OH)COOH
Molar Mass192.12 g/mol
HS Code2918 14 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point200 °C (1013 hPa) (rozklad)
Density1.67 g/cm3 (20 °C)
Melting Point153 °C (rozklad)
pH value1.7 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (25 °C)
Bulk density560 kg/m3
Solubility1330 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Potkan 3000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H319: Spôsobuje vážne podráždenie očí.
H335: Môže spôsobiť podráždenie dýchacích ciest.
Precautionary Statement(s)P261: Zabráňte vdychovaniu prachu.
P264: Po manipulácii starostlivo umyte pokožku.
P271: Používajte iba na voľnom priestranstve alebo v dobre vetranom priestore.
P280: Noste ochranné okuliare/ ochranu tváre.
P304 + P340 + P312: PO VDÝCHNUTÍ: Presuňte osobu na čerstvý vzduch a umožnite jej pohodlne dýchať. Pri zdravotných problémoch volajte NÁRODNÉ TOXIKOLOGICKÉ INFORMAČNÉ CENTRUM/lekára.
P305 + P351 + P338: PO ZASIAHNUTÍ OČÍ: Niekoľko minút ich opatrne vyplachujte vodou. Ak používate kontaktné šošovky a je to možné, odstráňte ich. Pokračujte vo vyplachovaní.
Signal WordPozor
RTECSGE7350000
Storage class10 - 13 Iné kvapaliny a tuhé látky
WGKWGK 1 mierne ohrozujúce vody
Safety Information
Categories of dangerdráždivá
Product Usage Statements
Storage and Shipping Information
StorageSkladujte pri +15°C až +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
Identity (IR-spectrum)passes test
Identity (wet chemistry)passes test
Appearancewhite to almost white, fine powder
Appearance of solution (200 g/l; water)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
Chloride (Cl)≤ 5 ppm
Sulfate (SO₄)≤ 50 ppm
Heavy metals (as Pb)≤ 5 ppm
Al (Aluminium)≤ 0.2 ppm
As (Arsenic)≤ 1 ppm
Ca (Calcium)passes test
Oxalates (as C₂H₂O₄)≤ 360 ppm
Oxalate (C₂H₂O₄) (ChP)passes test
Residual solvents (ICH Q3C)excluded by manufacturing process
Readily carbonisable substancepasses test
Sulfated ash (600 °C)≤ 0.05 %
Water (according to Karl Fischer)≤ 0.5 %
Total aerobic microbial count (TAMC)≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
Candida albicans (absent in 1 g)passes test
Escherichia coli (absent in 1 g)passes test
Pseudomonas aeruginosa (absent in 1 g)passes test
Salmonella (absent in 10 g)passes test
Staphylococcus aureus (absent in 1 g)passes test
DNases (Exo- and endonucleases)not detectable
RNasesnot detectable
Bacterial endotoxins< 10

Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, ChP, JP, USP
Global Trade Item Number
Catalogue Number GTIN
1370020001 04027269358273
1370021000 04027269358235
1370025000 04027269061890
1370029012 04027269077419
1370029029 04027269061418
1370029500 04027269354121

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Kyselina citrónová MSDS

Title

Safety Data Sheet (SDS) 

Kyselina citrónová Certificates of Analysis

Product Number PackagingSpecificationLot Number
1370020001 Kartónová krabicaPDF Specification Document
1370021000 Plastová flašaPDF Specification Document
1370025000 Plastová flašaPDF Specification Document
1370029012 Plastové vedroPDF Specification Document
1370029029 Dvojité PE vreckoPDF Specification Document
1370029500 Big BagPDF Specification Document

Certificates

Title