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218776 Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem

The Caspase-9 Inhibitor II, Cell-Permeable controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.

Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LEHD-CHO, Cell-permeable

Primary Target: caspase-4, caspase-5, caspase-9
218776
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₇H₁₆₂N₂₂O₂₅

Products

Catalogue NumberPackaging Qty/Pack
218776-1MG Sklená flaša 1 mg
Description
OverviewA potent, cell-permeable, and reversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
Catalogue Number218776
Brand Family Calbiochem®
SynonymsLEHD-CHO, Cell-permeable
References
ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Product Information
ATP CompetitiveN
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₉₇H₁₆₂N₂₂O₂₅
Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-4, caspase-5, caspase-9
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
218776-1MG 07790788048617

Documentation

Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem Certificates of Analysis

TitleLot Number
218776

References

Reference overview
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-June-2008 RFH
SynonymsLEHD-CHO, Cell-permeable
DescriptionA potent, cell-permeable and reversible inhibitor or caspase-9.
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.