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14-711 Casein Kinase 1γ1 Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human Casein Kinase 1γ1, amino acids 25-355, for use in Kinase Assays.

14-711
10 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-711
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCasein Kinase 1γ1 Protein, active, 10 µg
OverviewN-terminal 6His-tagged, recombinant, human Casein Kinase 1γ1, amino acids 25-355
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human Casein Kinase 1γ1, amino acids 25-355, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryCasein kinase I is the most abundant serine/threonine kinase in eukaryotic cell extracts. Multiple isoforms of the enzyme exist. The gamma-1 isoform is involved in growth and morphogenesis of eukaryotic cells.[supplied by OMIM]
Gene Symbol
  • CSNK1G1
Protein TargetCK1γ1
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCK1
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q9HCP0 # Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
SIZE: 422 amino acids; 48511 Da
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: Q9HCP0 ## Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. & Contains 1 protein kinase domain.
Molecular Weight41.9kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of 200μM KRRRALS(p)VASLPGL
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-711 04053252282546

Documentation