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216100 Carboplatin - CAS 41575-94-4 - Calbiochem

An analog of Cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

Carboplatin - CAS 41575-94-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin

Primary Target: Potent antitumor activity
216100
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
41575-94-4C₆H₁₂N₂O₄Pt

Products

Catalogue NumberPackaging Qty/Pack
216100-25MG Plastová ampulka 25 mg
Description
OverviewAn analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.

Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
Catalogue Number216100
Brand Family Calbiochem®
Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
References
ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
Product Information
CAS number41575-94-4
ATP CompetitiveN
FormWhite solid
Hill FormulaC₆H₁₂N₂O₄Pt
Chemical formulaC₆H₁₂N₂O₄Pt
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPotent antitumor activity
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSTP2300000
Safety Information
R PhraseR: 20/21/22-42/43-46-61

Harmful by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause heritable genetic damage.
May cause harm to the unborn child.
S PhraseS: 22-26-36/37/39-45-53

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
216100-25MG 04055977219265

Documentation

Carboplatin - CAS 41575-94-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Carboplatin - CAS 41575-94-4 - Calbiochem Certificates of Analysis

TitleLot Number
216100

References

Reference overview
Hall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-July-2014 JSW
Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
DescriptionAn analog of cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
FormWhite solid
CAS number41575-94-4
RTECSTP2300000
Chemical formulaC₆H₁₂N₂O₄Pt
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O with 5% Glucose (10 mg/mL)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful & Carcinogenic / Teratogenic
Merck USA index14, 1822
ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.