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212402 Carbacyclin

Stable, synthetic, carbacyclic analog of prostacyclin with similar spectrum of activity but is only 10% as potent.

Carbacyclin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Carbacyclic PGI₂

212402
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
69552-46-1C₂₁H₃₄O₄
Description
Overview

This product has been discontinued.





Stable, synthetic, carbacyclic analog of prostacyclin with similar spectrum of activity but is only 10% as potent. Activates adenylate cyclase via G-protein coupled PGI2 receptors. Mimics effects of naturally-occurring prostacyclin.
Catalogue Number212402
Brand Family Calbiochem®
SynonymsCarbacyclic PGI₂
References
ReferencesIto, Y., et al. 1994. Atherosclerosis 110, 69.
Sawai, T., et al. 1993. J. Biol. Chem. 268, 1995.
Turner, J.T., et al. 1992. J. Pharmacol. Exp. Ther. 263, 708.
Karim, S.M.M., et al. 1981. Prostaglandin Med. 6, 521.
Aiken, J.W., et al. 1980. Prostaglandins 19, 629.
Product Information
CAS number69552-46-1
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₁H₃₄O₄
Chemical formulaC₂₁H₃₄O₄
ReversibleN
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetActivates adenylate cyclase
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
212402 0

Documentation

Carbacyclin MSDS

Title

Safety Data Sheet (SDS) 

Carbacyclin Certificates of Analysis

TitleLot Number
212402

References

Reference overview
Ito, Y., et al. 1994. Atherosclerosis 110, 69.
Sawai, T., et al. 1993. J. Biol. Chem. 268, 1995.
Turner, J.T., et al. 1992. J. Pharmacol. Exp. Ther. 263, 708.
Karim, S.M.M., et al. 1981. Prostaglandin Med. 6, 521.
Aiken, J.W., et al. 1980. Prostaglandins 19, 629.

Brochure

Title
Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-May-2008 RFH
SynonymsCarbacyclic PGI₂
DescriptionStable, synthetic carbacyclic analog of prostacyclin that mimics the effects of naturally occurring prostacyclin, but is 10% as potent. Activates adenylate cyclase via G-protein coupled PGI2 receptors.
FormWhite solid
CAS number69552-46-1
Chemical formulaC₂₁H₃₄O₄
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityEthanol, EtOAc, or Acetone
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Harmful
ReferencesIto, Y., et al. 1994. Atherosclerosis 110, 69.
Sawai, T., et al. 1993. J. Biol. Chem. 268, 1995.
Turner, J.T., et al. 1992. J. Pharmacol. Exp. Ther. 263, 708.
Karim, S.M.M., et al. 1981. Prostaglandin Med. 6, 521.
Aiken, J.W., et al. 1980. Prostaglandins 19, 629.