Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

07-436-AF488 Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate

This Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Histones Gene Symbol: HIST3H3, H3FT UniProt Number: Q16695
07-436-AF488
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue Number07-436-AF488
DescriptionAnti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate
Alternate Names
  • Histone H3.1t
  • H3/t
  • H3t
  • H3/g
Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-436.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit Alexa Fluor® 488 conjugated antibody in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate is validated for use in ICC for the detection of monomethyl Histone H3 (Lys4).
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenLinear peptide corresponding to Histone H3 monomethylated at Lys4.
Concentration0.5 mg/mL
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Vertebrates based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST3H3
  • H3FT
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~17 kDa observed (Refer to Cat. No. 07-436)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemisty Analysis in HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected monomethyl Histone H3 (Lys4) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
07-436-AF488 04053252972867

Documentation

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate MSDS

Title

Safety Data Sheet (SDS) 

Anti-monomethyl Histone H3 (Lys4) Antibody, Alexa Fluor® 488 Conjugate Certificates of Analysis

TitleLot Number
Anti-monomethyl Histone H3 (Lys4), Alexa Fluor® 488 Conjugate - Q2411273 Q2411273
Anti-monomethyl Histone H3 (Lys4), Alexa Fluor® 488 Conjugate - 3419563 3419563
Anti-monomethyl Histone H3 (Lys4), Alexa Fluor® 488 Conjugate - 3953588 3953588
Anti-monomethyl Histone H3 (Lys4), Alexa Fluor® 488 Conjugate -2845033 2845033

Related Products & Applications

Product Families

Conjugated Antibodies for Chromatin Analysis

EMD Millipore's Alexa Fluor® Conjugated Histone and puromycin antibodies are validated in immunocytochemistry. All EMD Millipore antibodies are based on the expertise of Upstate & Chemicon.
Learn More >>

Categories

Life Science Research > Antibodies and Assays > Primary Antibodies