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07-261-I Anti-mGluR2 Antibody

Anti-mGluR2 Antibody is an antibody against mGluR2 for use in Western Blotting, Immunoprecipitation.

Anti-mGluR2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Grm2, Gprc1b, Mglur2 UniProt Number: Q14BI2
07-261-I
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RWB, IPRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number07-261-I
Replaces07-261
DescriptionAnti-mGluR2 Antibody
Alternate Names
  • 07-261
  • Histone H2AX
  • H2a/x
  • Histone H2A.X
Background InformationThe metabotropic glutamate receptors belong to a family of G protein-coupled receptors that have been divided into 3 groups based on their sequence homology, putative signal transduction mechanisms, and pharmacologic properties. mGluR2 belongs to the Group II. It is widely expressed in different regions of fetal and the adult brain. Ligand binding to GluR2 induces a conformation change in the receptor, which triggers signaling to modulate the activity of down-stream effectors, mainly via the inhibition of adenylate cyclase activity. Activation of mGluR2 leads to inhibition of glutamate release at the synaptic junction
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-mGluR2 Antibody is an antibody against mGluR2 for use in Western Blotting, Immunoprecipitation.
Key Applications
  • Western Blotting
  • Immunoprecipitation
Application NotesImmunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated mGlur2 in 500 µg of rat brain microsomal prep.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of mouse mGlur2.
EpitopeCytoplasmic domain
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Rat
Species Reactivity NoteRat. Predicted to react with Mouse based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • Grm2
  • Gprc1b
  • Mglur2
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~95/200 kDa observed. The lower band corresponds to the calculated molecular weight of mGluR2 (~100 kDa) and the upper band is likely a receptor dimer and frequently appears in immunoblots of mGluRs (Reid and Romano, 2001; Romano et al., 1996).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in rat brain microsomal prep.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected mGlur2 in 10 µg of rat brain microsomal prep.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
07-261-I 04055977134452

Documentation

Anti-mGluR2 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-mGluR2 Antibody Certificates of Analysis

TitleLot Number
Anti-mGluR2 - 3174750 3174750
Anti-mGluR2 - 3202198 3202198
Anti-mGluR2 - 3863480 3863480
Anti-mGluR2 - 3980761 3980761
Anti-mGluR2 -Q2519464 Q2519464
Anti-mGluR2 Polyclonal Antibody 3050591

Brochure

Title
NPI Flyer- Epigenetics and Nuclear Function Feature
New Products - Antibodies, Small Molecule, Inhibitors
Pathways and Biomarkers of Glutamatergic Synapse Flyer

Technical Info

Title
White Paper: Further considerations of antibody validation and usage.