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AB10343 Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7)

AB10343
50 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbSerumPolyclonal Antibody
Description
Catalogue NumberAB10343
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7)
Alternate Names
  • 3,4-catechol estrogen specific
  • UDP glucuronosyltransferase 2 family, polypeptide B7
  • UDP glycosyltransferase 2 family, polypeptide B7
  • UDP-glucuronosyltransferase 2B7
  • UDP-glucuronyltransferase, family 2, beta-7
Background InformationUGT2B7 (UDP-Glucuronosyltransferase-2B7) is a phase II metabolism isoenzyme active in the liver, kidneys, gastrointestinal tract and brain.It is found on the endoplasmic reticulum and nuclear membranes of cells. UGT2B7 is the major isoform for the metabolism of morphine to the main metabolites.
References
Product Information
FormatSerum
PresentationRaw rabbit serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect UGT2B7 (UDP-Glycosyltransferase 2B family) using this Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7) validated for use in WB.
Key Applications
  • Western Blotting
Application NotesWestern Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant human UGT2B7 protein.
Biological Information
ImmunogenRecombinant human UGT2B7
Epitopea.a S80–V122
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.[supplied by OMIM]
Gene Symbol
  • EC 2.4.1.17
  • UDPGT
  • UDPGTh-2
  • UGT2B9
  • UGTB2B9
UniProt Number
Molecular Weight61 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by Western Blot on baculovirus expressed recombinant human UGT2B7 protein.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 12 months from date of receipt.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB10343 04053252362729

Documentation

Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7) MSDS

Title

Safety Data Sheet (SDS) 

Anti-UGT2B7 Antibody (UDP-Glycosyltransferase 2B family, polypeptide 7) Certificates of Analysis

TitleLot Number
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family, polypeptide 7) - 2145027 2145027
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family, polypeptide 7) - 2048743 2048743
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family, polypeptide 7) - 2952577 2952577
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family, polypeptide 7) - NG1556735 NG1556735
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family, polypeptide 7) Polyclonal Antibody 3153999
Anti-UGT2B7 (UDP-Glycosyltransferase 2B family,polypeptide 7) -2679443 2679443
Anti-UGT2B7 -2794790 2794790