Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABN774 Anti-TDP-43 Antibody, clone DB9

Detect TDP-43 using this Anti-TDP-43 Antibody, clone DB9 validated for use in western blotting & IHC.

Anti-TDP-43 Antibody, clone DB9 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurodegenerative Diseases Gene Symbol: TARDBP, TDP43 UniProt Number: Q13148
MABN774
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN774
DescriptionAnti-TDP-43 Antibody, clone DB9
Alternate Names
  • TAR DNA-binding protein 43
  • TDP-43
  • TDP43
  • TAR DNA binding protein-43
Background InformationTAR DNA-binding protein 43 (TDP-43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in TDP-43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect TDP-43 using this Anti-TDP-43 Antibody, clone DB9 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TDP-43 in human cerebellum, pancreas, and thalamus tissues.
Biological Information
ImmunogenThe antibody was raised against an immunogen consisting of His-tagged recombinant protein corresponding to amino acid residues 208-414 of human TDP-43.
CloneDB9
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TARDBP
  • TDP43
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~43 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TDP-43 in 10 µg of SH-SY-5Y cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN774 04053252946059

Documentation

Anti-TDP-43 Antibody, clone DB9 MSDS

Title

Safety Data Sheet (SDS) 

Anti-TDP-43 Antibody, clone DB9 Certificates of Analysis

TitleLot Number
Anti-TDP-43, clone DB9 - 3205457 3205457
Anti-TDP-43, clone DB9 - 3483445 3483445
Anti-TDP-43, clone DB9 - 3604765 3604765
Anti-TDP-43, clone DB9 - 3724694 3724694
Anti-TDP-43, clone DB9 - 3839157 3839157
Anti-TDP-43, clone DB9 - 3879502 3879502
Anti-TDP-43, clone DB9 - 4108272 4108272
Anti-TDP-43, clone DB9 - 4163450 4163450
Anti-TDP-43, clone DB9 - Q2364942 Q2364942
Anti-TDP-43, clone DB9 -2796263 2796263
Show more