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MABC603 Anti-SERPINB5 Antibody, clone 5C6.2

This Anti-SERPINB5 Antibody, clone 5C6.2 is validated for use in Western Blotting, Immunohistochemistry (Paraffin) for the detection of SERPINB5.

Anti-SERPINB5 Antibody, clone 5C6.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: SERPINB5, PI5 UniProt Number: P36952
MABC603
100 μg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC603
DescriptionAnti-SERPINB5 Antibody, clone 5C6.2
Alternate Names
  • Serpin B5
  • SERPINB5
  • Maspin
  • Peptidase inhibitor 5
  • PI-5
Background InformationSerpin B5 (UniProt P36952; also known as Maspin, Peptidase inhibitor 5, PI-5) is encoded by the SERPINB5 (also known as PI5) gene (Gene ID 5268) in human. Serpin B5/Maspin is an evolutionarily conserved serine protease inhibitor that induces apoptosis and inhibits the motility of breast cancer cells. DNA hypermethylation and histone deacetylation lead to silencing of the SERPINB5 gene in human breast cancer.
References
Product Information
FormatPurified
HS Code3002 15 90
PresentationPurified mouse monoclonal IgG2bκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-SERPINB5 Antibody, clone 5C6.2 is validated for use in Western Blotting, Immunohistochemistry (Paraffin) for the detection of SERPINB5.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesWestern Blotting Analysis: 1.0 µg/mL from a representative lot detected SERPINB5 in 10 µg of HT-1080 and HT-29 cell lysates.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected SERPINB5 in human breast tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the C-terminal of human SERPINB5.
EpitopeC-terminal half
Clone5C6.2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityDoes not detect spliced isoform 2 (UniProt P36952-2).
IsotypeIgG2bκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • SERPINB5
  • PI5
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~42 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in HCT116 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SERPINB5 in 10 µg of HCT116 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC603 04055977182736

Documentation

Anti-SERPINB5 Antibody, clone 5C6.2 MSDS

Title

Safety Data Sheet (SDS) 

Anti-SERPINB5 Antibody, clone 5C6.2 Certificates of Analysis

TitleLot Number
Anti-SERPINB5, clone 5C6.2 - 3378585 3378585
Anti-SERPINB5, clone 5C6.2 - 3496476 3496476
Anti-SERPINB5, clone 5C6.2 -Q2589910 Q2589910

Technical Info

Title
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.