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AB9279 Anti-Rhodopsin Antibody

Anti-Rhodopsin Antibody detects level of Rhodopsin & has been published & validated for use in IH(P).

Anti-Rhodopsin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Sensory & PNS Gene Symbol: RHO, RP4, rhodopsin, MGC138311, Opsin-2, OPN2, MGC138309, Rhodopsin UniProt Number: P08100
AB9279
50 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9279
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Rhodopsin Antibody
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin. Liquid in PBS, with less than 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Rhodopsin Antibody detects level of Rhodopsin & has been published & validated for use in IH(P).
Key Applications
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry on paraffin embedded tissue sections.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from the 2nd extracellular domain of human Rhodopsin.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Rhodopsin.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryRetinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Gene Symbol
  • RHO
  • RP4
  • rhodopsin
  • MGC138311
  • Opsin-2
  • OPN2
  • MGC138309
  • Rhodopsin
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P08100 # Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
SIZE: 348 amino acids; 38893 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Rod shaped photoreceptor cells which mediates vision in dim light.
PTM: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
DISEASE: SwissProt: P08100 # Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4) [MIM:180380]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP4 inheritance is autosomal dominant. & Defects in RHO are a cause of retinitis pigmentosa autosomal recessive (ARRP) [MIM:268000]. & Defects in RHO are a cause of autosomal dominant congenital stationary night blindness 1 (CSNBAD1) [MIM:610445]; also known as rhodopsin-related congenital stationary night blindness. Congenital stationary night blindness is a nonprogressive retinal disorder characterized by impaired night vision and ocular symptoms such as myopia, hyperopia, nystagmus and reduced visual acuity.
SIMILARITY: SwissProt: P08100 ## Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Availability by Geography
  • This product is not available for sale in Japan.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9279 04053252269899

Documentation

Anti-Rhodopsin Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Rhodopsin Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI- RHODOPSIN - 2538631 2538631
RABBIT ANTI- RHODOPSIN - 3199166 3199166
RABBIT ANTI- RHODOPSIN - 3442513 3442513
RABBIT ANTI- RHODOPSIN - 3519308 3519308
RABBIT ANTI- RHODOPSIN - 3677711 3677711
RABBIT ANTI- RHODOPSIN - 3992241 3992241
RABBIT ANTI- RHODOPSIN - 4085560 4085560
RABBIT ANTI- RHODOPSIN - 4124271 4124271
RABBIT ANTI- RHODOPSIN - 4169249 4169249
RABBIT ANTI- RHODOPSIN - 4187710 4187710
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Data Sheet

Title
RABBIT ANTI- RHODOPSIN AFFINITY PURIFIED