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MAB8599 Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Infectious Diseases Research Sub-Category: Infectious Diseases - Viral
MAB8599
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HELISA, FC, IF, WBMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB8599
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A
Alternate Names
  • RSV Fusion
Background InformationRSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
References
Product Information
FormatPurified
HS Code3002 15 90
Control
  • RSV Control Slides, Catalogue Number 5012-5
PresentationProtein A Purified immunoglobulin in 0.02M phosphate, 0.25M NaCl, 0.1% NaN3 pH 7.6
Quality LevelMQ300
Applications
ApplicationAnti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.
Key Applications
  • ELISA
  • Flow Cytometry
  • Immunofluorescence
  • Western Blotting
Application NotesIndirect immunofluorescence.

ELISA

Immunoblotting: (using purified F protein preparations, clone identified a ~70kDa band, Tripp, RA et al 2003)

Final working dilutions must be determined by end user.
Biological Information
ImmunogenA2 RSV virus cell extract
Epitopeall type A & B strains
Clone131-2A
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityReacts with RSV fusion protein, specifically epitope F1a of RSV F-protein {Sominina AA, et al Vestn Ross Akad Med Nauk. 1995;(9):49-54} found on all A & B strains of RSV.
IsotypeIgG2aκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Purification MethodProtein A Purfied
Molecular Weight~70 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB8599 04053252316654

Documentation

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A MSDS

Title

Safety Data Sheet (SDS) 

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A Certificates of Analysis

TitleLot Number
MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2382151 2382151
MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2441924 2441924
MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2453211 2453211
MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2153026 2153026
MOUSE ANTI-RSV FUSION PROTEIN - 3213889 3213889
MOUSE ANTI-RSV FUSION PROTEIN - 3235652 3235652
MOUSE ANTI-RSV FUSION PROTEIN - 3599028 3599028
MOUSE ANTI-RSV FUSION PROTEIN - 3703220 3703220
MOUSE ANTI-RSV FUSION PROTEIN - 3778051 3778051
MOUSE ANTI-RSV FUSION PROTEIN - 3843755 3843755
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References

Reference overviewApplicationPub Med ID
Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes
Agrawal, Amit, et al
J Virol, 79:8625-8 (2005)  2004

Flow Cytometry15956604 15956604
Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis
Harcourt, Jennifer L, et al
J Infect Dis, 190:1936-40 (2004)  2004

15529257 15529257
The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P
Tripp, Ralph A, et al
J Virol, 77:6580-4 (2003)  2003

Immunoblotting (Western)12743318 12743318
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
Haynes, L M, et al
J Virol, 75:10730-7 (2001)  2001

Immunofluorescence11602714 11602714
Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice
Tripp, R A, et al
J Virol, 73:7099-107 (1999)  1998

10438795 10438795
Characteristics of monoclonal antibodies to RS virus in immunoenzyme and immunofluorescence techniques
Sominina, A A, et al
Vestn Akad Med Nauk SSSR, :49-54 (1995)  1994

7580416 7580416
Subgrouping of respiratory syncytial virus strains from Australia and Papua New Guinea by biological and antigenic characteristics
Hierholzer, J C, et al
Arch Virol, 136:133-47 (1994)  1993

Enzyme Immunoassay (ELISA)8002781 8002781