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AB10627 Anti-Omentin Antibody

Anti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.

Anti-Omentin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Lipid Metabolism & Weight Regulation Gene Symbol: ITLN1, hIntL, HL1, INTL, Omentin, HL-1, omentin, ITLN, LFR, intelectin, FLJ20022 UniProt Number: Q8WWA0
AB10627
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HELISA, WBRbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB10627
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Omentin Antibody
Background InformationA calcium-dependent lectin with affinity for furanosides, such as galactofuranosyl in bacterial arabinogalactans. 30kD of apparent molecular weight of Omentin migrate at 40-kD under reducing conditions due to glycosylation. Omentin, a novel visceral fat depot-specific secretory protein, enhance insulin-stimulated glucose transport in subcutaneous as well as omental adipocytes and may therefore be implicated in the pathogenesis of obesity.
References
Product Information
FormatPurified
PresentationLiquid in PBS, pH7.4. Contains no preservatives.
Quality LevelMQ100
Applications
ApplicationAnti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.
Key Applications
  • ELISA
  • Western Blotting
Application NotesWestern blot: 1:2,000-1:5,000 using ECL. Reacted with the ~40kDa Omentin His-tagged protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.

ELISA, direct and indirect: 1:2,000-1:5,000.
Biological Information
ImmunogenSynthetic peptide: TVGDRWSSQQGSKADYPEGDG, corresponding to amino acids 95-115 of Human Omentin.
EpitopeAmino acids 95-115 of Human Omentin.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Omentin in western blotting.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ITLN1
  • hIntL
  • HL1
  • INTL
  • Omentin
  • HL-1
  • omentin
  • ITLN
  • LFR
  • intelectin
  • FLJ20022
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q8WWA0 # May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
SIZE: 313 amino acids; 34962 Da
SUBUNIT: Homotrimer; disulfide-linked.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
TISSUE SPECIFICITY: Specifically expressed in the small intestine. Also found the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid; and to a lesser degree in the uterus, spleen, prostate, lymph node and thymus.
DEVELOPMENTAL STAGE: Found in fetal small intestine and thymus.
PTM: N-glycosylated.
SIMILARITY: SwissProt: Q8WWA0 ## Contains 1 fibrinogen C-terminal domain.
Molecular Weight30-40 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB10627 04053252476136

Documentation

Anti-Omentin Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Omentin Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-HUMAN OMENTIN - 3063424 3063424
RABBIT ANTI-HUMAN OMENTIN - 3204925 3204925
RABBIT ANTI-HUMAN OMENTIN - 3237539 3237539
RABBIT ANTI-HUMAN OMENTIN -2638061 2638061
RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY 3139181
RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY 2920357
RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY - 2204872 2204872
RABBIT ANTI-HUMAN OMENTIN POLYCLONAL ANTIBODY - 2364197 2364197

References

Reference overviewPub Med ID
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action
Yang, Rong-Ze, et al
Am J Physiol Endocrinol Metab, 290:E1253-61 (2006)  2005

16531507 16531507
Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall
Tsuji, S, et al
J Biol Chem, 276:23456-63 (2001)  2001

11313366 11313366