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MABC674 Anti-LPL Antibody, clone 2C5

MABC674
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABC674
DescriptionAnti-LPL Antibody, clone 2C5
Alternate Names
  • Lipoprotein lipase
  • HDLCQ11
Background InformationLipoprotein lipase (LPL) is encoded by the LPL/LIPD gene in humans and is a lipase that localizes to the plasma membrane of the microvilli of hepatocytes and the luminal surface of endothelial cells in capillaries. It is expressed in a wide variety of tissues from fat and heart to muscle and mammary glands. It can also be found in the blood bound to lipoproteins. Its function is to hydrolyze triglycerides from the blood and other sources into free fatty acids; LPL also acts as receptor and binding factor for lipoprotein uptake and allows for the catalysis of VLDL from the blood. Expression and regulation of LPL differ by tissue type, some factors such as insulin can stimulate LPL expression in fat tissues, where as insulin down regulates LPL expression on muscle. Recently because serum triglyceride levels are linked with the development of cancer, LPL has become a target for cancer prevention and therapy because LPL catalyzes plasma triglycerides leading to lower levels, it is thought that LPL assisted therapy could be useful in preventing or treating cancers. EMD-Millipore’s Anti-LPL mouse monoclonal antibody has been tested on western blots using HeLa cell lysates.
References
Product Information
FormatAscites
HS Code3002 15 90
Control
  • Hela cell lysate
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-LPL Antibody, clone 2C5 is a mouse monoclonal antibody & validated for use in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of human LPL expressed in E. Coli.
Clone2C5
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • LPL
  • LIPD
Purification MethodUnpurified
UniProt Number
Molecular Weight~53 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Hela cell lysate.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected LPL in Hela cell lysate.

Optimal working dilutions must be determined by end user.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC674 04053252916403

Documentation

Anti-LPL Antibody, clone 2C5 MSDS

Title

Safety Data Sheet (SDS) 

Anti-LPL Antibody, clone 2C5 Certificates of Analysis

TitleLot Number
Anti-LPL, clone 2C5 - VP1401150 VP1401150
Anti-LPL, clone 2C5 - VP2404100 VP2404100
Anti-LPL, clone 2C5 -VP1506294 VP1506294
Anti-LPL, clone 2C5 -VP1507157 VP1507157
Anti-LPL, clone 2C5 -VP1507210 VP1507210
Anti-LPL, clone 2C5 -VP1511203 VP1511203
Anti-LPL, clone 2C5 -VP1601123 VP1601123
Anti-LPL, clone 2C5 -VP1605070 VP1605070
Anti-LPL, clone 2C5 Monoclonal Antibody VP1701206
Anti-LPL, clone 2C5 Monoclonal Antibody VP1711102