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407313 Anti-Integrin αIIb Mouse mAb (283.16B7)

This Anti-Integrin αIIb Mouse mAb (283.16B7) is validated for use in ELISA, Flow Cytometry, Paraffin Sections for the detection of Integrin αIIb.

Anti-Integrin αIIb Mouse mAb (283.16B7) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-CD41

407313
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
407313-100UL Plastová ampulka 100 ul
Description
OverviewRecognizes the αIIb integrin chain.
  • Antibody Target Gene Symbol: ITGA2B
  • Target Synonym: AI172977, ALPHA 2B, alphaIIb, CD41, CD41A, CD41B, GP2B, GPIIB, GTA, HPA3, INTEGRIN ALPHA 2B, Itga2b, LOC685269
  • Entrez Gene Name: integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Hu Entrez ID: 16399
  • Rat Entrez ID:
    • Catalogue Number407313
    Brand Family Calbiochem®
    SynonymsAnti-CD41
    References
    ReferencesHynes, R.O. 1992. Cell. 69, 11.
    Phillips, D.R., et al. 1991. Cell. 65, 359.
    Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
    Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
    Hynes, R.O. 1987. Cell. 45, 549.
    Product Information
    FormLiquid
    FormulationUndiluted ascites.
    PreservativeNone
    Quality LevelMQ100
    Applications
    Key Applications Enzyme-Linked Immunosorbent Assay
    Flow Cytometry
    Paraffin Sections
    Application NotesELISA (see comments)
    Flow Cytometry (1:50-1:100)
    Paraffin Sections (1:50-1:100)
    Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
    Biological Information
    Immunogenintegrin αIIb from M21-L-llb melanoma cells
    ImmunogenHuman
    Clone283.16B7
    HostMouse
    IsotypeIgG₁
    Species Reactivity
    • Human
    Antibody TypeMonoclonal Antibody
    Physicochemical Information
    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Storage and Shipping Information
    Ship Code Dry Ice Only
    Toxicity Standard Handling
    Storage -20°C
    Avoid freeze/thaw Avoid freeze/thaw
    Do not freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Packaging Information
    Transport Information
    Supplemental Information
    Specifications
    Global Trade Item Number
    Catalogue Number GTIN
    407313-100UL 04055977188264

    Documentation

    Anti-Integrin αIIb Mouse mAb (283.16B7) MSDS

    Title

    Safety Data Sheet (SDS) 

    Anti-Integrin αIIb Mouse mAb (283.16B7) Certificates of Analysis

    TitleLot Number
    407313

    References

    Reference overview
    Hynes, R.O. 1992. Cell. 69, 11.
    Phillips, D.R., et al. 1991. Cell. 65, 359.
    Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
    Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
    Hynes, R.O. 1987. Cell. 45, 549.
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision06-August-2007 RFH
    SynonymsAnti-CD41
    ApplicationELISA (see comments)
    Flow Cytometry (1:50-1:100)
    Paraffin Sections (1:50-1:100)
    DescriptionMouse monoclonal antibody supplied as undiluted ascites. Recognizes the αIIb integrin chain.
    BackgroundThe integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated α and β subunits. CD41 consists of two disulfide-linked subunits, GPIIba and GPIIbb. CD41 non-covalently associates with CD61 (integrin β3) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.
    HostMouse
    Immunogen speciesHuman
    Immunogenintegrin αIIb from M21-L-llb melanoma cells
    Clone283.16B7
    IsotypeIgG₁
    Specieshuman
    FormLiquid
    FormulationUndiluted ascites.
    PreservativeNone
    CommentsVariables associated with assay conditions will dictate the proper working dilution.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Toxicity Standard Handling
    ReferencesHynes, R.O. 1992. Cell. 69, 11.
    Phillips, D.R., et al. 1991. Cell. 65, 359.
    Albelda, S.M. and Buck, C.A. 1990. FASEB J. 4, 2868.
    Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol. 3, 179.
    Hynes, R.O. 1987. Cell. 45, 549.