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MABN319 Anti-Coronin-1A, clone 2E4.1 Antibody

Anti-Coronin-1A, clone 2E4.1 Antibody is an antibody against Coronin-1A for use in Immunohistochemistry and Immunocytochemistry.

Anti-Coronin-1A, clone 2E4.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CORO1A, CORO1 UniProt Number: P31146
MABN319
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN319
DescriptionAnti-Coronin-1A, clone 2E4.1 Antibody
Alternate Names
  • Coronin-1A
  • Coronin-like protein A
  • Clipin-A
  • Coronin-like protein p57
  • Tryptophan aspartate-containing coat protein
  • TACO
Background InformationCoronin-1A (also known as clipin-A, coronin-1, coronin-like protein, Acoronin-like protein p57, tryptophan aspartate-containing coat protein) is a cytoplasmic protein encoded by the CORO1A gene in human (also known as CLABP, CLIPINA, HCORO1, IMD8, TACO). It is a member of the WD repeat protein family of proteins that are reported to be involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Coronin-1A is reported to be a component of the phagosome coat that is normally released prior to maturation into lysosomes. Mycobacteria are reported to evade host defense by recruiting and retaining coronin-1A on phagosomes, while in coronin-1A-lacking macrophages, mycobacteria are readily transported to lysosomes for degradation (PMID 10338208).
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-Coronin-1A, clone 2E4.1 Antibody is an antibody against Coronin-1A for use in Immunohistochemistry and Immunocytochemistry.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Coronin-1A in human cerebellum and human thalamus tissue.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human Coronin-1A.
Clone2E4.1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • CORO1A
  • CORO1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~51 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Coronin-1A in 10 µg of Jurkat cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN319 04055977159325