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AB15468 Anti-Choline Acetyltransferase Antibody

Anti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IC, IH.

Anti-Choline Acetyltransferase Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors, Neuronal & Glial Markers Gene Symbol: CHAT, ChAT, CMS1A2, CHOACTase, CMS1A, EC 2.3.1.6 UniProt Number: P28329
AB15468
500 µL  
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Overview

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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MICC, IHCChAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB15468
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Choline Acetyltransferase Antibody
Alternate Names
  • ChAT
References
Product Information
FormatAffinity Purified
PresentationLiquid in PBS, pH 7.2 with 0.02% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IC, IH.
Key Applications
  • Immunocytochemistry
  • Immunohistochemistry
Application NotesImmunohistochemistry: 1:1,000-1:2,000 using 2% paraformaldehyde fixed tissue.

Immunocytochemistry: 1:1,000-1:2,000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenSynthetic peptide corresponding to human/mouse ChAT protein.
HostChicken
SpecificityCholine acetyltransferase [ChAT]
Species Reactivity
  • Mouse
Species Reactivity NoteOther species have not yet been tested. It is expected that the antibody will also react with human due to immunogen sequence similarity.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryCholinergic systems are implicated in numerous neurologic functions. Alteration in some cholinergic neurons may account for the disturbances of Alzheimer disease. The protein encoded by this gene synthesizes the neurotransmitter acetylcholine. Alternative splice variants have been found that contain alternative 5' untranslated exons. Three of the four described splice variants encode identical 69 kDa proteins while one variant encodes both the 69 kDa and a larger 82 kDa protein.
Gene Symbol
  • CHAT
  • ChAT
  • CMS1A2
  • CHOACTase
  • CMS1A
  • EC 2.3.1.6
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P28329 # Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
SIZE: 748 amino acids; 82568 Da
DISEASE: SwissProt: P28329 # Defects in CHAT are the cause of familial infantile myasthenia gravis 2 (FIMG2) [MIM:254210, 254200]; also known as CMS-EA. FIMG2 patients have myasthenic symptoms since birth or early infancy, negative tests for anti-AChR antibodies, and abrupt episodic crises with increased weakness, bulbar paralysis, and apnea precipitated by undue exertion, fever, or excitement. Inheritance is autosomal recessive.
SIMILARITY: SwissProt: P28329 ## Belongs to the carnitine/choline acetyltransferase family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
Packaging Information
Material Size500 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB15468 04053252401275

Documentation

Anti-Choline Acetyltransferase Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Choline Acetyltransferase Antibody Certificates of Analysis

TitleLot Number
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY - 2441970 2441970
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY - 2446718 2446718
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) - 3959193 3959193
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) - 4070154 4070154
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY 3124179
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY 3011665
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY 3156103
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY 2924873
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY - 2017260 2017260
CHICKEN ANTI-CHOLINE ACETYLTRANSFERASE (ChAT) POLYCLONAL ANTIBODY - 2037212 2037212
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References

Reference overviewPub Med ID
Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditory nuclei.
SM Maricich, A Xia, EL Mathes, VY Wang, JS Oghalai, B Fritzsch, HY Zoghbi
The Journal of neuroscience : the official journal of the  29  11123-11133  2009

Show Abstract Full Text Article		19741118 19741118

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Categories

Life Science Research > Antibodies and Assays > Primary Antibodies