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MAB5580 Anti-Arrestin Antibody, visual

Detect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB.

Anti-Arrestin Antibody, visual MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Sensory & PNS Gene Symbol: ARR3, Arrestin-C, CAR, ARRX, C-arrestin, cArr UniProt Number: P79260
MAB5580
100 µL  
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Overview

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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
B, Gt, H, Po, R, ShIHC, IP, WBMAscitesMonoclonal Antibody
Description
Catalogue NumberMAB5580
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Arrestin Antibody, visual
Alternate Names
  • S-antigen
  • rod arrestin
Background InformationVisual arrestin is a 48 kDa protein expressed exclusively in retinal photoreceptor cells where it regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual arrestin is the major pathogenetic autoantigen in human autoimmume imflammatory eye disease.
Product Information
FormatAscites
PresentationAscites fluid. Liquid.
Quality LevelMQ100
Applications
ApplicationDetect Arrestin using this Anti-Arrestin Antibody, visual validated for use in IH, IP & WB.
Key Applications
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blotting
Application NotesWestern blot: 48kDa

Immunohistochemistry

Immunopurification of arrestin

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenPorcine visual arrestin.
HostMouse
SpecificityVisual arrestin. The antibody has not been tested for reactivity to arrestin in other tissues.
IsotypeIgG1
Species Reactivity
  • Bovine
  • Goat
  • Human
  • Pig
  • Rat
  • Sheep
Antibody TypeMonoclonal Antibody
Gene Symbol
  • ARR3
  • Arrestin-C
  • CAR
  • ARRX
  • C-arrestin
  • cArr
UniProt Number
UniProt SummaryFunction: Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
Tissue specificity: Retina and pineal gland. Also expressed in the anterior tissues such as the ciliary epithelium and iris epithelium.
Involvement in disease: S-antigen induces autoimmune uveitis.
Miscellaneous: Arrestin binds calcium By similarity.
Sequence similarities: Belongs to the arrestin family.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
MAB5580 04053252357855