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MAB312-AF647 Anti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor® 647 Conjugate

Anti-A2B5 Antibody, clone A2B5-105, Alexa Fluor® 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.

Anti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor® 647 Conjugate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience UniProt Number: Not Applicable
MAB312-AF647
100 µL  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MaFC, ICCMAlexaFluor®647Monoclonal Antibody
Description
Catalogue NumberMAB312-AF647
DescriptionAnti-A2B5 Antibody, clone A2B5-105 Antibody, Alexa Fluor® 647 Conjugate
Alternate Names
  • F12A2B5
  • 105
Background InformationA2B5 (also known as F12A2B5) is a cell surface ganglioside expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells. It is highly expressed in embryonic and neonatal tissue, but in the adult mammalian brain its expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ). Hence, A2B5 is considered as a marker for immature glial-committed precursors, which are permanently generated in the SVZ. Its expression is also considered as a marker for various cancers, including astrocytoma, glioma, pancreatic islet tumors, and squamous cell carcinoma. Explants from A2B5+ tumor cells display a typical progenitor morphology and clearly indicate their immature state. Tumors expressing A2B5 antigen exhibit higher rates of recurrence.
References
Product Information
FormatAlexaFluor®647
PresentationPurified mouse IgM Alexa Fluor® 647 conjugate in PBS with 1.5% BSA and 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-A2B5 Antibody, clone A2B5-105, Alexa Fluor® 647 Conjugate Cat. No. MAB312-AF647, is a highly specific mouse monoclonal antibody that targets A2B5 and has been tested in Immunocytochemistry and Flow Cytometry.
Key Applications
  • Flow Cytometry
  • Immunocytochemistry
Application NotesFlow Cytometry Analysis: 1:400 dilution from a representative lot immunostained the surface of PC12 cells.

The unconjugated antibody (Cat. No. MAB312) is also available for flow cytometry, immunocytochemistry, immunofluorescence, and immunohistochemistry applications.
Biological Information
ImmunogenEmbryonic chicken retinal cells.
CloneA2B5-105
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityThis monoclonal antibody detects A2B5 in mammalian cells.
IsotypeIgM
Species Reactivity
  • Mammals
Species Reactivity NoteMammals.
Antibody TypeMonoclonal Antibody
Purification MethodAmmonium sulfate.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by immunocytochemistry of PC12 cells.

Immunocytochemistry Analysis: A 1:100 Dilution of this antibody immunostained the surface of PC12 cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB312-AF647 04054839134364