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116813 Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-2ʹ-monobutyryl-, Rp-Isomer, Sodium Salt

Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-2ʹ-monobutyryl-, Rp-Isomer, Sodium Salt MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Rp-8-Br-MB-cAMPS, Na

116813
  
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Overview

Replacement Information
Description
Overview

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A cell-permeable and reversible inhibitor of protein kinase A that is reported to block the excitatory effect of 8-Bromo-cGMP and to inhibit the basal Ca2+ currents in smooth muscle. More lipophilic and cell permeable than Rp-8-Bromo-cAMP (Cat. No. 116816).
Note: 5 µmol = 2.58 mg.
Catalogue Number116813
Brand Family Calbiochem®
SynonymsRp-8-Br-MB-cAMPS, Na
References
ReferencesRuiz-Velasco, V., et al. 1998. Circ. Res. 82, 557.
Product Information
DeclarationSold under license of Patent DE 3,802,865.4 issued to BIOLOG LSI.
FormWhite lyophilized solid
Hill FormulaC₁₄H₁₆BrN₅O₆PS · Na
Chemical formulaC₁₄H₁₆BrN₅O₆PS · Na
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetPKA
Secondary targetBasal Ca2+ current in smooth muscle
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 1 month at -20°C or up to 6 months at -70°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
116813 0

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-Bromo-2ʹ-monobutyryl-, Rp-Isomer, Sodium Salt Certificates of Analysis

TitleLot Number
116813

References

Reference overview
Ruiz-Velasco, V., et al. 1998. Circ. Res. 82, 557.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2007 RFH
SynonymsRp-8-Br-MB-cAMPS, Na
DescriptionAn inhibitor of protein kinase A that also inhibits the basal Ca2+ currents in smooth muscle. Reported to block the excitatory effect of 8-Bromo-cGMP (Cat No. 203820). More lipophilic and cell-permeable than Rp-8-Br-cAMPS (Cat. No. 116816).
FormWhite lyophilized solid
Chemical formulaC₁₄H₁₆BrN₅O₆PS · Na
Structure formulaStructure formula
Purity≥97% by HPLC
SolubilityH₂O (10 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C or -70°C). Stock solutions are stable for up to 1 month at -20°C or up to 6 months at -70°C.
Toxicity Standard Handling
ReferencesRuiz-Velasco, V., et al. 1998. Circ. Res. 82, 557.