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152228 AEG3482

AEG3482 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide, 281D

152228
  
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Overview

Key Spec Table

CAS #Empirical Formula
63735-71-7C₁₀H₈N₄O₂S₂
Description
Overview

This product has been discontinued.





A cell-permeable imidazothiadiazole compound that activates cellular transcription factor HSF1 by binding to HSP90 and disrupting its association with HSF1. Shown to induce HSF1-dependent expression of HSP70 and HSP25 and effectively block NRAGE- and p75NTR-mediated JNK activation and apoptosis in PC12 cells in a dose-dependent manner (>90% inhibition at 40 µM).
Catalogue Number152228
Brand Family Calbiochem®
Synonyms6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide, 281D
References
ReferencesSalehi, A.H., et al. 2006. Chem. Biol. 13, 213.
Product Information
CAS number63735-71-7
FormLight yellow solid
Hill FormulaC₁₀H₈N₄O₂S₂
Chemical formulaC₁₀H₈N₄O₂S₂
Structure formula ImageStructure formula Image
Biological Information
Purity≥98% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
152228 0