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101500 AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem

101500
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Overview

Key Spec Table

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S · HCl

Products

Catalogue NumberPackaging Qty/Pack
101500-100MG Sklená flaša 100 mg
101500-1GM Sklená flaša 1 gm
101500-500MG Plastová ampulka 500 mg
101500-50MG Sklená flaša 50 mg
Description
OverviewSpecific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications. Also available as a 50 mM solution in H2O (Cat. No. 508436).
Catalogue Number101500
Brand Family Calbiochem®
Synonyms4-(2-Aminoethyl)benzenesulfonylfluoride, HCl
Application Data
References
ReferencesCitron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
Product Information
CAS number30827-99-7
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₈H₁₀FNO₂S · HCl
Chemical formulaC₈H₁₀FNO₂S · HCl
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetchymotrypsin
Purity>97% by HPLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Aqueous stock solutions are stable for up to 2 months at 4°C. Slight hydrolysis occurs at alkaline pH (8-9).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
101500-100MG 04055977226317
101500-1GM 04055977226300
101500-500MG 04055977226348
101500-50MG 04055977226331