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480354 7S NGF, Mouse Submaxillary Glands

7S NGF, Mouse Submaxillary Glands MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7S Nerve Growth Factor

480354
  
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Overview

Replacement Information
Description
Overview

This product has been discontinued.



Native 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits: (α: β: γ): 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
Catalogue Number480354
Brand Family Calbiochem®
Synonyms7S Nerve Growth Factor
References
ReferencesBax, B., et al. 1997. Structure 5, 1275.
Shao, N., et al. 1993. Brain Res. 609, 338.
Varon, S., et al. 1972. Methods Neurochem. 3, 203.
Product Information
FormLyophilized
FormulationLyophilized from sterile H₂O.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
Physicochemical Information
ContaminantsEGF: none detected
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
480354 0

Documentation

7S NGF, Mouse Submaxillary Glands MSDS

Title

Safety Data Sheet (SDS) 

7S NGF, Mouse Submaxillary Glands Certificates of Analysis

TitleLot Number
480354

References

Reference overview
Bax, B., et al. 1997. Structure 5, 1275.
Shao, N., et al. 1993. Brain Res. 609, 338.
Varon, S., et al. 1972. Methods Neurochem. 3, 203.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-January-2010 JSW
Synonyms7S Nerve Growth Factor
DescriptionNative 7S nerve growth factor from mouse submaxillary glands. Promotes neuron survival and neurite outgrowth in newborn rat brain. Composed of three subunits (α:β:γ) 2:1:2. The α-subunit is an inactive serine proteinase and the γ-subunit is an active serine proteinase capable of processing the precursor form of β-NGF.
FormLyophilized
FormulationLyophilized from sterile H₂O.
ContaminantsEGF: none detected
Biological activityED₅₀: Determined by half maximal growth of PC12 cells. Please see vial label for lot-specific ED₅₀.
SolubilityNeutral (pH 7.0) buffers (1 mg/ml). The 7S NGF complex will dissociate in acidic or basic buffers, so it is critical that the pH of the reconstitution buffer be neutral.
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 2 weeks at -20°C.
Toxicity Standard Handling
Merck USA index14, 6477
ReferencesBax, B., et al. 1997. Structure 5, 1275.
Shao, N., et al. 1993. Brain Res. 609, 338.
Varon, S., et al. 1972. Methods Neurochem. 3, 203.