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505771 4-DAMP - CAS 1952-15-4 - Calbiochem

4-DAMP - CAS 1952-15-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP

Primary Target: Muscarinic Receptors
505771
  
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1952-15-4C₂₁H₂₆INO₂
Description
Overview

This product has been discontinued.



An antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
Catalogue Number505771
Brand Family Calbiochem®
Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
References
ReferencesKruse, C., et al., 2012. Nature. 482, 552.
Moriya, H., et al., 1999. Life Sci. 64, 2351.
Ehlert, J., 1996. Life Sci. 58, 1971.
Product Information
CAS number1952-15-4
FormWhite to off-white solid
Hill FormulaC₂₁H₂₆INO₂
Chemical formulaC₂₁H₂₆INO₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMuscarinic Receptors
Primary Target K<sub>i</sub>0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505771 0

Documentation

4-DAMP - CAS 1952-15-4 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Kruse, C., et al., 2012. Nature. 482, 552.
Moriya, H., et al., 1999. Life Sci. 64, 2351.
Ehlert, J., 1996. Life Sci. 58, 1971.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-October-2018 JSW
Synonyms1,1-Dimethyl-4-diphenylacetoxypiper­idinium iodide, Muscarinic Receptor Antagonist, 4-DAMP
DescriptionAn antagonist selective for mAChRs (Ki = 0.57, 7.3, 0.37, 0.72 and 0.55 nM at human M1, M2, M3, M4, and M5 receptors respectively). Used frequently in investigating the functional roles of M1 and M3 receptors in both central and peripheral nervous systems.
FormWhite to off-white solid
CAS number1952-15-4
Chemical formulaC₂₁H₂₆INO₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (100 mM) or Ethanol (25 mM)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKruse, C., et al., 2012. Nature. 482, 552.
Moriya, H., et al., 1999. Life Sci. 64, 2351.
Ehlert, J., 1996. Life Sci. 58, 1971.