Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

407306 γ-Interferon, Human, Recombinant, E. coli

γ-Interferon, Human, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
407306
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
407306-100UG Plastová ampulka 100 μg
Description
OverviewRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses.
Catalogue Number407306
Brand Family Calbiochem®
References
ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
Müller, U., et al. 1994. Science 264, 1918.
Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
Shuai, K., et al. 1993. Science 261, 1744.
Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
Product Information
FormLiquid
FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
407306-100UG 04055977188257

Documentation

γ-Interferon, Human, Recombinant, E. coli MSDS

Title

Safety Data Sheet (SDS) 

γ-Interferon, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
407306

References

Reference overview
Kohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
Müller, U., et al. 1994. Science 264, 1918.
Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
Shuai, K., et al. 1993. Science 261, 1744.
Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.

Citations

Title
  • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
  • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision05-June-2008 JSW
    DescriptionRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Expressed in and purified from E. coli.
    FormLiquid
    FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
    Concentration Label Please refer to vial label for lot-specific concentration
    Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
    Toxicity Standard Handling
    Merck USA index14, 4992
    ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
    Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
    Müller, U., et al. 1994. Science 264, 1918.
    Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
    Shuai, K., et al. 1993. Science 261, 1744.
    Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
    Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
    Citation
  • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
  • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
    		•